A Randomized Clinical Trial of Fecal Microbiota Transplant for Alcohol Use Disorder

Background and Aims Alcohol use disorder (AUD) is associated with microbial alterations that worsen with cirrhosis. Fecal microbiota transplant (FMT) could be a promising approach. Approach and Results In this phase 1, double‐blind, randomized clinical trial, patients with AUD‐related cirrhosis with...

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Veröffentlicht in:	Hepatology (Baltimore, Md.) Md.), 2021-05, Vol.73 (5), p.1688-1700
Hauptverfasser:	Bajaj, Jasmohan S., Gavis, Edith A., Fagan, Andrew, Wade, James B., Thacker, Leroy R., Fuchs, Michael, Patel, Samarth, Davis, Brian, Meador, Jill, Puri, Puneet, Sikaroodi, Masoumeh, Gillevet, Patrick M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adverse events Aged Alcohol Drinking - epidemiology Alcohol use Alcoholism - therapy Cirrhosis Clinical trials Cognition Craving Creatinine Demography Double-Blind Method Drinking behavior Fatty acids Fecal Microbiota Transplantation - methods Fecal microflora Feces Gastrointestinal Microbiome Hepatology Humans Lipopolysaccharides Liver cirrhosis Liver diseases Male Microbiota Middle Aged Placebos Quality of life Ruminococcaceae Surveys and Questionnaires Treatment Outcome
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