Anabolic steroid excess promotes hydroelectrolytic and autonomic imbalance in adult male rats: Is it enough to alter blood pressure?

•AS excess elicited kidney hypertrophy and increased renal AT1R mRNA levels.•AS excess increased Na+/water retention, K+ excretion, and plasma osmolarity.•Water and NaCl intake were distinctly altered by AS excess.•AS-induced autonomic imbalance was attenuated by icv losartan. The present study inve...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Steroids 2020-11, Vol.163, p.108711-108711, Article 108711
Hauptverfasser:	Seara, Fernando A.C., Pereira-Junior, Pedro P., Silva-Almeida, Claudio, Dos-Santos, Raoni C., Souza, Raquel N., Costa, César R.M., Domingos, Ainá E., Barbosa, Raiana A.Q., Ferraz, Ana P., Machado, André A.N., Ceccato, Vânia M., Takiya, Christina M., Ponte, Cristiano G., Reis, Luis C., Olivares, Emerson L., Nascimento, Jose H.M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Anabolic steroids Angiotensin II Autonomic imbalance Blood pressure Hydroelectrolytic imbalance Vascular reactivity
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!