Herba Cistanche (Rou Cong Rong): A Review of Its Phytochemistry and Pharmacology
Herba Cistanche, known as Rou Cong Rong in Chinese, is a very valuable Chinese herbal medicine that has been recorded in the Chinese Pharmacopoeia. Rou Cong Rong has been extensively used in clinical practice in traditional herbal formulations and has also been widely used as a health food supplemen...
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Veröffentlicht in: | Chemical & pharmaceutical bulletin 2020/08/01, Vol.68(8), pp.694-712 |
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description | Herba Cistanche, known as Rou Cong Rong in Chinese, is a very valuable Chinese herbal medicine that has been recorded in the Chinese Pharmacopoeia. Rou Cong Rong has been extensively used in clinical practice in traditional herbal formulations and has also been widely used as a health food supplement for a long time in Asian countries such as China and Japan. There are many bioactive compounds in Rou Cong Rong, the most important of which are phenylethanoid glycosides. This article summarizes the up-to-date information regarding the phytochemistry, pharmacology, processing, toxicity and safety of Rou Cong Rong to reveal its pharmacodynamic basis and potential therapeutic effects, which could be of great value for its use in future research. |
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Rou Cong Rong has been extensively used in clinical practice in traditional herbal formulations and has also been widely used as a health food supplement for a long time in Asian countries such as China and Japan. There are many bioactive compounds in Rou Cong Rong, the most important of which are phenylethanoid glycosides. This article summarizes the up-to-date information regarding the phytochemistry, pharmacology, processing, toxicity and safety of Rou Cong Rong to reveal its pharmacodynamic basis and potential therapeutic effects, which could be of great value for its use in future research.</description><identifier>ISSN: 0009-2363</identifier><identifier>EISSN: 1347-5223</identifier><identifier>DOI: 10.1248/cpb.c20-00057</identifier><identifier>PMID: 32741910</identifier><language>eng</language><publisher>Japan: The Pharmaceutical Society of Japan</publisher><subject>Animals ; Bioactive compounds ; Biocompatibility ; Cistanche - chemistry ; Cistanche - metabolism ; Dietary supplements ; Drugs, Chinese Herbal ; Formulations ; Gastrointestinal Microbiome - drug effects ; Glycosides ; Glycosides - chemistry ; Glycosides - isolation & purification ; Glycosides - pharmacology ; Glycosides - therapeutic use ; Herba Cistanche ; Herbal medicine ; Monoterpenes - chemistry ; Monoterpenes - isolation & purification ; Monoterpenes - pharmacology ; Monoterpenes - therapeutic use ; Natural & organic foods ; Oxidative Phosphorylation - drug effects ; Parkinson Disease - drug therapy ; Parkinson Disease - veterinary ; Pharmacodynamics ; Pharmacology ; phenylethanoid glycoside ; Phenylethyl Alcohol - chemistry ; Phytochemicals - chemistry ; Phytochemicals - pharmacology ; Phytochemicals - therapeutic use ; phytochemistry ; review ; Toxicity</subject><ispartof>Chemical and Pharmaceutical Bulletin, 2020/08/01, Vol.68(8), pp.694-712</ispartof><rights>2020 The Pharmaceutical Society of Japan</rights><rights>Copyright Japan Science and Technology Agency 2020</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c702t-38fe259bfa01203598516ac2d8aa4c4fa0ed3258a10aec3bc525493fb79163163</citedby><cites>FETCH-LOGICAL-c702t-38fe259bfa01203598516ac2d8aa4c4fa0ed3258a10aec3bc525493fb79163163</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,1877,27901,27902</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/32741910$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Lei, Huibo</creatorcontrib><creatorcontrib>Wang, Xinyu</creatorcontrib><creatorcontrib>Zhang, Yuhao</creatorcontrib><creatorcontrib>Cheng, Taofang</creatorcontrib><creatorcontrib>Mi, Rui</creatorcontrib><creatorcontrib>Xu, Xike</creatorcontrib><creatorcontrib>Zu, Xianpeng</creatorcontrib><creatorcontrib>Zhang, Weidong</creatorcontrib><creatorcontrib>bSchool of Pharmacy</creatorcontrib><creatorcontrib>Shanghai Jiao Tong University</creatorcontrib><creatorcontrib>dSchool of Pharmacy</creatorcontrib><creatorcontrib>Second Military Medical University</creatorcontrib><creatorcontrib>cSchool of Pharmacy</creatorcontrib><creatorcontrib>Anhui University of Chinese Medicine</creatorcontrib><creatorcontrib>Shanghai University of Traditional Chinese Medicine</creatorcontrib><creatorcontrib>aInstitute of Interdisciplinary Medical Sciences</creatorcontrib><title>Herba Cistanche (Rou Cong Rong): A Review of Its Phytochemistry and Pharmacology</title><title>Chemical & pharmaceutical bulletin</title><addtitle>Chem. Pharm. Bull.</addtitle><description>Herba Cistanche, known as Rou Cong Rong in Chinese, is a very valuable Chinese herbal medicine that has been recorded in the Chinese Pharmacopoeia. Rou Cong Rong has been extensively used in clinical practice in traditional herbal formulations and has also been widely used as a health food supplement for a long time in Asian countries such as China and Japan. There are many bioactive compounds in Rou Cong Rong, the most important of which are phenylethanoid glycosides. This article summarizes the up-to-date information regarding the phytochemistry, pharmacology, processing, toxicity and safety of Rou Cong Rong to reveal its pharmacodynamic basis and potential therapeutic effects, which could be of great value for its use in future research.</description><subject>Animals</subject><subject>Bioactive compounds</subject><subject>Biocompatibility</subject><subject>Cistanche - chemistry</subject><subject>Cistanche - metabolism</subject><subject>Dietary supplements</subject><subject>Drugs, Chinese Herbal</subject><subject>Formulations</subject><subject>Gastrointestinal Microbiome - drug effects</subject><subject>Glycosides</subject><subject>Glycosides - chemistry</subject><subject>Glycosides - isolation & purification</subject><subject>Glycosides - pharmacology</subject><subject>Glycosides - therapeutic use</subject><subject>Herba Cistanche</subject><subject>Herbal medicine</subject><subject>Monoterpenes - chemistry</subject><subject>Monoterpenes - isolation & purification</subject><subject>Monoterpenes - pharmacology</subject><subject>Monoterpenes - therapeutic use</subject><subject>Natural & organic foods</subject><subject>Oxidative Phosphorylation - drug effects</subject><subject>Parkinson Disease - drug therapy</subject><subject>Parkinson Disease - veterinary</subject><subject>Pharmacodynamics</subject><subject>Pharmacology</subject><subject>phenylethanoid glycoside</subject><subject>Phenylethyl Alcohol - chemistry</subject><subject>Phytochemicals - chemistry</subject><subject>Phytochemicals - pharmacology</subject><subject>Phytochemicals - therapeutic use</subject><subject>phytochemistry</subject><subject>review</subject><subject>Toxicity</subject><issn>0009-2363</issn><issn>1347-5223</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2020</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpdkU1rGzEQhkVpaVy3x16LoJfksOlotJJ2ewtL8wGBBtOehVbWOmvWK1dat_jfd2KnDhTECGYevTN6h7GPAi4FltUXv20vPUIBAMq8YjMhS1MoRPmazShXFyi1PGPvcl4DoAIj37IziaYUtYAZe7gNqXW86fPkRv8Y-Pki7ngTxxVfULj4yq_4Ivzuwx8eO343Zf7wuJ8ikRt6kvbcjUtKubRxPg5xtX_P3nRuyOHD8z1nP6-__Whui_vvN3fN1X3hDeBUyKoLqOq2cyAQpKorJbTzuKycK31J6bCUqConwAUvW69QlbXsWlMLLenM2flRd5vir13Ik6WBfBgGN4a4yxZLSb_XShtCP_-HruMujTQdUVgrZWqi56w4Uj7FnFPo7Db1G5f2VoB9stqS1Zastgerif_0rLprN2F5ov95S8DNEaBq790Qx6Efw0tvn83BRotwENUVVHShBV2XFoxAqYwGjaTUHJXWtKVVOLVyaer9EA6D6cpWT-E04EuVtmPDKP8CAKalVQ</recordid><startdate>20200801</startdate><enddate>20200801</enddate><creator>Lei, Huibo</creator><creator>Wang, Xinyu</creator><creator>Zhang, Yuhao</creator><creator>Cheng, Taofang</creator><creator>Mi, Rui</creator><creator>Xu, Xike</creator><creator>Zu, Xianpeng</creator><creator>Zhang, Weidong</creator><general>The Pharmaceutical Society of Japan</general><general>Pharmaceutical Society of Japan</general><general>Japan Science and Technology Agency</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7TK</scope><scope>7TM</scope><scope>7U9</scope><scope>H94</scope><scope>7X8</scope></search><sort><creationdate>20200801</creationdate><title>Herba Cistanche (Rou Cong Rong): A Review of Its Phytochemistry and Pharmacology</title><author>Lei, Huibo ; Wang, Xinyu ; Zhang, Yuhao ; Cheng, Taofang ; Mi, Rui ; Xu, Xike ; Zu, Xianpeng ; Zhang, Weidong</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c702t-38fe259bfa01203598516ac2d8aa4c4fa0ed3258a10aec3bc525493fb79163163</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2020</creationdate><topic>Animals</topic><topic>Bioactive compounds</topic><topic>Biocompatibility</topic><topic>Cistanche - chemistry</topic><topic>Cistanche - metabolism</topic><topic>Dietary supplements</topic><topic>Drugs, Chinese Herbal</topic><topic>Formulations</topic><topic>Gastrointestinal Microbiome - drug effects</topic><topic>Glycosides</topic><topic>Glycosides - chemistry</topic><topic>Glycosides - isolation & purification</topic><topic>Glycosides - pharmacology</topic><topic>Glycosides - therapeutic use</topic><topic>Herba Cistanche</topic><topic>Herbal medicine</topic><topic>Monoterpenes - chemistry</topic><topic>Monoterpenes - isolation & purification</topic><topic>Monoterpenes - pharmacology</topic><topic>Monoterpenes - therapeutic use</topic><topic>Natural & organic foods</topic><topic>Oxidative Phosphorylation - drug effects</topic><topic>Parkinson Disease - drug therapy</topic><topic>Parkinson Disease - veterinary</topic><topic>Pharmacodynamics</topic><topic>Pharmacology</topic><topic>phenylethanoid glycoside</topic><topic>Phenylethyl Alcohol - chemistry</topic><topic>Phytochemicals - chemistry</topic><topic>Phytochemicals - pharmacology</topic><topic>Phytochemicals - therapeutic use</topic><topic>phytochemistry</topic><topic>review</topic><topic>Toxicity</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Lei, Huibo</creatorcontrib><creatorcontrib>Wang, Xinyu</creatorcontrib><creatorcontrib>Zhang, Yuhao</creatorcontrib><creatorcontrib>Cheng, Taofang</creatorcontrib><creatorcontrib>Mi, Rui</creatorcontrib><creatorcontrib>Xu, Xike</creatorcontrib><creatorcontrib>Zu, Xianpeng</creatorcontrib><creatorcontrib>Zhang, Weidong</creatorcontrib><creatorcontrib>bSchool of Pharmacy</creatorcontrib><creatorcontrib>Shanghai Jiao Tong University</creatorcontrib><creatorcontrib>dSchool of Pharmacy</creatorcontrib><creatorcontrib>Second Military Medical University</creatorcontrib><creatorcontrib>cSchool of Pharmacy</creatorcontrib><creatorcontrib>Anhui University of Chinese Medicine</creatorcontrib><creatorcontrib>Shanghai University of Traditional Chinese Medicine</creatorcontrib><creatorcontrib>aInstitute of Interdisciplinary Medical Sciences</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Neurosciences Abstracts</collection><collection>Nucleic Acids Abstracts</collection><collection>Virology and AIDS Abstracts</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>MEDLINE - Academic</collection><jtitle>Chemical & pharmaceutical bulletin</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Lei, Huibo</au><au>Wang, Xinyu</au><au>Zhang, Yuhao</au><au>Cheng, Taofang</au><au>Mi, Rui</au><au>Xu, Xike</au><au>Zu, Xianpeng</au><au>Zhang, Weidong</au><aucorp>bSchool of Pharmacy</aucorp><aucorp>Shanghai Jiao Tong University</aucorp><aucorp>dSchool of Pharmacy</aucorp><aucorp>Second Military Medical University</aucorp><aucorp>cSchool of Pharmacy</aucorp><aucorp>Anhui University of Chinese Medicine</aucorp><aucorp>Shanghai University of Traditional Chinese Medicine</aucorp><aucorp>aInstitute of Interdisciplinary Medical Sciences</aucorp><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Herba Cistanche (Rou Cong Rong): A Review of Its Phytochemistry and Pharmacology</atitle><jtitle>Chemical & pharmaceutical bulletin</jtitle><addtitle>Chem. 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subjects | Animals Bioactive compounds Biocompatibility Cistanche - chemistry Cistanche - metabolism Dietary supplements Drugs, Chinese Herbal Formulations Gastrointestinal Microbiome - drug effects Glycosides Glycosides - chemistry Glycosides - isolation & purification Glycosides - pharmacology Glycosides - therapeutic use Herba Cistanche Herbal medicine Monoterpenes - chemistry Monoterpenes - isolation & purification Monoterpenes - pharmacology Monoterpenes - therapeutic use Natural & organic foods Oxidative Phosphorylation - drug effects Parkinson Disease - drug therapy Parkinson Disease - veterinary Pharmacodynamics Pharmacology phenylethanoid glycoside Phenylethyl Alcohol - chemistry Phytochemicals - chemistry Phytochemicals - pharmacology Phytochemicals - therapeutic use phytochemistry review Toxicity |
title | Herba Cistanche (Rou Cong Rong): A Review of Its Phytochemistry and Pharmacology |
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