Characteristics and Outcomes of Hospitalized Young Adults with Mild Covid -19
Stormy course has been reported among hospitalized adults with COVID-19 in high- and middle-income countries. To assess clinical outcomes in consecutively hospitalized patients with mild covid-19 in India we performed a study. We developed a case registry of successive patients admitted with suspect...
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| Veröffentlicht in: | Journal of the Association of Physicians of India 2020-08, Vol.68 (8), p.62-65 |
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| container_title | Journal of the Association of Physicians of India |
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| creator | Sharma, Arvind Kumar Ahmed, Asrar Baig, Vaseem Naheed Dhakar, Prahlad Dalela, Gaurav Kacker, Sudhanshu Panwar, Vasim Raja Panwar, Raja Babu Gupta, Rajeev |
| description | Stormy course has been reported among hospitalized adults with COVID-19 in high- and middle-income countries. To assess clinical outcomes in consecutively hospitalized patients with mild covid-19 in India we performed a study.
We developed a case registry of successive patients admitted with suspected covid-19 infection to our hospital (n=501). Covid-19 was diagnosed using reverse transcriptase polymerase chain reaction (RT-PCR). Demographic, clinical, investigations details and outcomes were recorded. Descriptive statistics are presented.
Covid-19 was diagnosed in 234 (46.7%) and data compared with 267 (53.3%) negative controls. Mean age of covid-19 patients was 35.1±16.6y, 59.4% were 40y (9.1±5.2) compared to 40-59y (11.3±6.1) and ≥60y (16.4±13.3) (p=0.001).
This hospital-based registry shows that mildly symptomatic or asymptomatic young covid-19 patients have excellent prognosis. |
| format | Article |
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We developed a case registry of successive patients admitted with suspected covid-19 infection to our hospital (n=501). Covid-19 was diagnosed using reverse transcriptase polymerase chain reaction (RT-PCR). Demographic, clinical, investigations details and outcomes were recorded. Descriptive statistics are presented.
Covid-19 was diagnosed in 234 (46.7%) and data compared with 267 (53.3%) negative controls. Mean age of covid-19 patients was 35.1±16.6y, 59.4% were <40y and 64% men. Symptoms were in less than 10% and comorbidities were in 4-8%. History of BCG vaccination was in 49% cases vs 10% controls. Cases compared to controls had significantly greater white cell (6.96+1.89 vs 6.12+1.69x109 cells/L) and lower lymphocyte count (1.98+0.79 vs 2.32+0.91x109 cells/L). No radiological and electrocardiographic abnormality was observed. All these were isolated or quarantined in the hospital and observed. Covid-19 patients received hydroxychloroquine and azithromycin according to prevalent guidelines. One patient needed oxygen support while hospital course was uncomplicated in the rest. All were discharged alive. Conversion to virus negative status was in 10.2±6.4 days and was significantly lower in age >40y (9.1±5.2) compared to 40-59y (11.3±6.1) and ≥60y (16.4±13.3) (p=0.001).
This hospital-based registry shows that mildly symptomatic or asymptomatic young covid-19 patients have excellent prognosis.</description><identifier>ISSN: 0004-5772</identifier><identifier>PMID: 32738843</identifier><language>eng</language><publisher>India</publisher><subject>Betacoronavirus ; Comorbidity ; Coronavirus Infections - diagnosis ; Coronavirus Infections - physiopathology ; COVID-19 ; Female ; Hospitalization ; Humans ; India ; Male ; Pandemics ; Pneumonia, Viral - diagnosis ; Pneumonia, Viral - physiopathology ; Prognosis ; SARS-CoV-2 ; Young Adult</subject><ispartof>Journal of the Association of Physicians of India, 2020-08, Vol.68 (8), p.62-65</ispartof><rights>Journal of the Association of Physicians of India 2011.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/32738843$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Sharma, Arvind Kumar</creatorcontrib><creatorcontrib>Ahmed, Asrar</creatorcontrib><creatorcontrib>Baig, Vaseem Naheed</creatorcontrib><creatorcontrib>Dhakar, Prahlad</creatorcontrib><creatorcontrib>Dalela, Gaurav</creatorcontrib><creatorcontrib>Kacker, Sudhanshu</creatorcontrib><creatorcontrib>Panwar, Vasim Raja</creatorcontrib><creatorcontrib>Panwar, Raja Babu</creatorcontrib><creatorcontrib>Gupta, Rajeev</creatorcontrib><title>Characteristics and Outcomes of Hospitalized Young Adults with Mild Covid -19</title><title>Journal of the Association of Physicians of India</title><addtitle>J Assoc Physicians India</addtitle><description>Stormy course has been reported among hospitalized adults with COVID-19 in high- and middle-income countries. To assess clinical outcomes in consecutively hospitalized patients with mild covid-19 in India we performed a study.
We developed a case registry of successive patients admitted with suspected covid-19 infection to our hospital (n=501). Covid-19 was diagnosed using reverse transcriptase polymerase chain reaction (RT-PCR). Demographic, clinical, investigations details and outcomes were recorded. Descriptive statistics are presented.
Covid-19 was diagnosed in 234 (46.7%) and data compared with 267 (53.3%) negative controls. Mean age of covid-19 patients was 35.1±16.6y, 59.4% were <40y and 64% men. Symptoms were in less than 10% and comorbidities were in 4-8%. History of BCG vaccination was in 49% cases vs 10% controls. Cases compared to controls had significantly greater white cell (6.96+1.89 vs 6.12+1.69x109 cells/L) and lower lymphocyte count (1.98+0.79 vs 2.32+0.91x109 cells/L). No radiological and electrocardiographic abnormality was observed. All these were isolated or quarantined in the hospital and observed. Covid-19 patients received hydroxychloroquine and azithromycin according to prevalent guidelines. One patient needed oxygen support while hospital course was uncomplicated in the rest. All were discharged alive. Conversion to virus negative status was in 10.2±6.4 days and was significantly lower in age >40y (9.1±5.2) compared to 40-59y (11.3±6.1) and ≥60y (16.4±13.3) (p=0.001).
This hospital-based registry shows that mildly symptomatic or asymptomatic young covid-19 patients have excellent prognosis.</description><subject>Betacoronavirus</subject><subject>Comorbidity</subject><subject>Coronavirus Infections - diagnosis</subject><subject>Coronavirus Infections - physiopathology</subject><subject>COVID-19</subject><subject>Female</subject><subject>Hospitalization</subject><subject>Humans</subject><subject>India</subject><subject>Male</subject><subject>Pandemics</subject><subject>Pneumonia, Viral - diagnosis</subject><subject>Pneumonia, Viral - physiopathology</subject><subject>Prognosis</subject><subject>SARS-CoV-2</subject><subject>Young Adult</subject><issn>0004-5772</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2020</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNo1kLFOwzAURT2AaAn8AvLIEsn1c2JnrCKgSK26wMAUOfYzNXLqEDsg-HqQKNNdzjnDPSNLxpgoKyn5glym9MYYNAD8giyAS1BKwJLs2oOetMk4-ZS9SVQfLd3P2cQBE42ObmIafdbBf6OlL3E-vtK1nUNO9NPnA935YGkbP7yl5aq5IudOh4TXpy3I8_3dU7spt_uHx3a9LccVr3NpGVrEupeVBqMa43qNTgjTQ68UqysrG6OlYw5sbzirQTQcoOLIERVDAQW5_euOU3yfMeVu8MlgCPqIcU4dF8BYI-SvWpCbEzr3A9punPygp6_u_wL4AS-XVs4</recordid><startdate>202008</startdate><enddate>202008</enddate><creator>Sharma, Arvind Kumar</creator><creator>Ahmed, Asrar</creator><creator>Baig, Vaseem Naheed</creator><creator>Dhakar, Prahlad</creator><creator>Dalela, Gaurav</creator><creator>Kacker, Sudhanshu</creator><creator>Panwar, Vasim Raja</creator><creator>Panwar, Raja Babu</creator><creator>Gupta, Rajeev</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>7X8</scope></search><sort><creationdate>202008</creationdate><title>Characteristics and Outcomes of Hospitalized Young Adults with Mild Covid -19</title><author>Sharma, Arvind Kumar ; Ahmed, Asrar ; Baig, Vaseem Naheed ; Dhakar, Prahlad ; Dalela, Gaurav ; Kacker, Sudhanshu ; Panwar, Vasim Raja ; Panwar, Raja Babu ; Gupta, Rajeev</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-p126t-d0edee6b75a3c89cfbaef44cb3b88065d79ca7f0f3dbc20634923352e2ee80e43</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2020</creationdate><topic>Betacoronavirus</topic><topic>Comorbidity</topic><topic>Coronavirus Infections - diagnosis</topic><topic>Coronavirus Infections - physiopathology</topic><topic>COVID-19</topic><topic>Female</topic><topic>Hospitalization</topic><topic>Humans</topic><topic>India</topic><topic>Male</topic><topic>Pandemics</topic><topic>Pneumonia, Viral - diagnosis</topic><topic>Pneumonia, Viral - physiopathology</topic><topic>Prognosis</topic><topic>SARS-CoV-2</topic><topic>Young Adult</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Sharma, Arvind Kumar</creatorcontrib><creatorcontrib>Ahmed, Asrar</creatorcontrib><creatorcontrib>Baig, Vaseem Naheed</creatorcontrib><creatorcontrib>Dhakar, Prahlad</creatorcontrib><creatorcontrib>Dalela, Gaurav</creatorcontrib><creatorcontrib>Kacker, Sudhanshu</creatorcontrib><creatorcontrib>Panwar, Vasim Raja</creatorcontrib><creatorcontrib>Panwar, Raja Babu</creatorcontrib><creatorcontrib>Gupta, Rajeev</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of the Association of Physicians of India</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Sharma, Arvind Kumar</au><au>Ahmed, Asrar</au><au>Baig, Vaseem Naheed</au><au>Dhakar, Prahlad</au><au>Dalela, Gaurav</au><au>Kacker, Sudhanshu</au><au>Panwar, Vasim Raja</au><au>Panwar, Raja Babu</au><au>Gupta, Rajeev</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Characteristics and Outcomes of Hospitalized Young Adults with Mild Covid -19</atitle><jtitle>Journal of the Association of Physicians of India</jtitle><addtitle>J Assoc Physicians India</addtitle><date>2020-08</date><risdate>2020</risdate><volume>68</volume><issue>8</issue><spage>62</spage><epage>65</epage><pages>62-65</pages><issn>0004-5772</issn><abstract>Stormy course has been reported among hospitalized adults with COVID-19 in high- and middle-income countries. To assess clinical outcomes in consecutively hospitalized patients with mild covid-19 in India we performed a study.
We developed a case registry of successive patients admitted with suspected covid-19 infection to our hospital (n=501). Covid-19 was diagnosed using reverse transcriptase polymerase chain reaction (RT-PCR). Demographic, clinical, investigations details and outcomes were recorded. Descriptive statistics are presented.
Covid-19 was diagnosed in 234 (46.7%) and data compared with 267 (53.3%) negative controls. Mean age of covid-19 patients was 35.1±16.6y, 59.4% were <40y and 64% men. Symptoms were in less than 10% and comorbidities were in 4-8%. History of BCG vaccination was in 49% cases vs 10% controls. Cases compared to controls had significantly greater white cell (6.96+1.89 vs 6.12+1.69x109 cells/L) and lower lymphocyte count (1.98+0.79 vs 2.32+0.91x109 cells/L). No radiological and electrocardiographic abnormality was observed. All these were isolated or quarantined in the hospital and observed. Covid-19 patients received hydroxychloroquine and azithromycin according to prevalent guidelines. One patient needed oxygen support while hospital course was uncomplicated in the rest. All were discharged alive. Conversion to virus negative status was in 10.2±6.4 days and was significantly lower in age >40y (9.1±5.2) compared to 40-59y (11.3±6.1) and ≥60y (16.4±13.3) (p=0.001).
This hospital-based registry shows that mildly symptomatic or asymptomatic young covid-19 patients have excellent prognosis.</abstract><cop>India</cop><pmid>32738843</pmid><tpages>4</tpages></addata></record> |
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| subjects | Betacoronavirus Comorbidity Coronavirus Infections - diagnosis Coronavirus Infections - physiopathology COVID-19 Female Hospitalization Humans India Male Pandemics Pneumonia, Viral - diagnosis Pneumonia, Viral - physiopathology Prognosis SARS-CoV-2 Young Adult |
| title | Characteristics and Outcomes of Hospitalized Young Adults with Mild Covid -19 |
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