Toward quantitative neuroimaging biomarkers for Friedreich's ataxia at 7 Tesla: Susceptibility mapping, diffusion imaging, R2 and R1 relaxometry

Friedreich's ataxia (FRDA) is a rare genetic disorder leading to degenerative processes. So far, no effective treatment has been found. Therefore, it is important to assist the development of medication with imaging biomarkers reflecting disease status and progress. Ten FRDA patients (mean age...

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Veröffentlicht in:Journal of neuroscience research 2020-11, Vol.98 (11), p.2219-2231
Hauptverfasser: Straub, Sina, Mangesius, Stephanie, Emmerich, Julian, Indelicato, Elisabetta, Nachbauer, Wolfgang, Degenhardt, Katja S., Ladd, Mark E., Boesch, Sylvia, Gizewski, Elke R.
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Sprache:eng
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