Sex differences in kappa opioid receptor antinociception is influenced by the number of X chromosomes in mouse
Kappa opioid receptor (KOR) agonists produce robust analgesia with minimal abuse liability and are considered promising pharmacological agents to manage chronic pain and itch. The KOR system is also notable for robust differences between the sexes, with females exhibiting lower analgesic response th...
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Veröffentlicht in: | Journal of neuroscience research 2022-01, Vol.100 (1), p.183-190 |
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