Maduramicin triggers methuosis-like cell death in primary chicken myocardial cells

•Excessive cytoplasm vacuolations and cell death induced by maduramicin.•Distinct from apoptosis and autophagy: cytoplasmic vacuolization-related cell death.•Vacuolar-H+-ATPase is necessary for maduramicin-induced cytoplasmic vacuolization and cell death.•Maduramicin induces methuosis-like cell deat...

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Veröffentlicht in:	Toxicology letters 2020-10, Vol.333, p.105-114
Hauptverfasser:	Gao, Xiuge, Ruan, Xiangchun, Ji, Hui, Peng, Lin, Qiu, Yawei, Yang, Dan, Song, Xinhao, Ji, Chunlei, Guo, Dawei, Jiang, Shanxiang
Format:	Artikel
Sprache:	eng
Schlagworte:	Cardiotoxicity Chicken myocardial cells Cytoplasmic vacuolization Maduramicin Methuosis Nonapoptotic cell death
Online-Zugang:	Volltext
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