Transcription factor NRF2 as a promising therapeutic target for Alzheimer’s disease

Oxidative stress is considered as one of the pathogenesis of Alzheimer’s disease (AD) and plays an important role in the occurrence and development of AD. Nuclear factor erythroid 2 related factor 2 (NRF2) is a key regulatory of oxidative stress defence. There is growing evidence indicating the rela...

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Veröffentlicht in:	Free radical biology & medicine 2020-11, Vol.159, p.87-102
Hauptverfasser:	Qu, Zhuo, Sun, Jiachen, Zhang, Wannian, Yu, Jianqiang, Zhuang, Chunlin
Format:	Artikel
Sprache:	eng
Schlagworte:	Alzheimer’s disease Ferroptosis Neuroinflammation NRF2 Oxidative stress Proteostasis
Online-Zugang:	Volltext
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