Association of SAPAP3 Allelic Variants With Symptom Dimensions and Pharmacological Treatment Response in Obsessive-Compulsive Disorder

Though several SAPAP3 gene knockout studies in mice have implicated its role in compulsivity, human studies have failed to demonstrate its association with obsessive-compulsive disorder (OCD). We examined the association between allelic variants of a single nucleotide polymorphism in the SAPAP3 gene...

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Veröffentlicht in:	Experimental and clinical psychopharmacology 2022-02, Vol.30 (1), p.106-112
Hauptverfasser:	Naaz, Safoora, Balachander, Srinivas, Srinivasa Murthy, Nithyananda, MS, Bhagyalakshmi, Sud, Reeteka, Saha, Priyanka, Narayanaswamy, Janardhanan C., Reddy YC, Janardhan, Jain, Sanjeev, Purushottam, Meera, Viswanath, Biju
Format:	Artikel
Sprache:	eng
Schlagworte:	Alleles Animals Drug Therapy Female Genes Genotype Human Male Mice Nerve Tissue Proteins - genetics Nucleotides Obsessive Compulsive Disorder Obsessive-Compulsive Disorder - drug therapy Obsessive-Compulsive Disorder - genetics Phenotypes Polymorphism Psychiatric Status Rating Scales Serotonin Reuptake Inhibitors Serotonin Uptake Inhibitors Treatment Resistant Disorders
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