Pseudoephedrine alleviates atopic dermatitis-like inflammatory responses in vivo and in vitro

Atopic dermatitis is a chronic inflammatory disease characterized by eczematous lesions and has become a serious health problem worldwide. Pseudoephedrine (PSE) is a nasal decongestant to treat the common cold. PSE has been reported that is beneficial to allergic diseases. However, whether PSE has t...

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Veröffentlicht in:	Life sciences (1973) 2020-10, Vol.258, p.118139-118139, Article 118139
Hauptverfasser:	Chen, Xiaolei, Lin, Jiacheng, Liang, Qingsong, Chen, Xiaoyin, Wu, Zhongping
Format:	Artikel
Sprache:	eng
Schlagworte:	1-Chloro-2,4-dinitrobenzene Allergic diseases Atopic dermatitis CD4 antigen Common cold Cytokines Decongestants Dermatitis DNCB Gelatinase B HaCaT Hydration Immunoglobulin E Inflammatory diseases Interleukin 13 Interleukin 23 Interleukin 4 Interleukin 6 Keratinocytes Lesions Leukocyte migration Leukocytes (neutrophilic) MAPKs Monocyte chemoattractant protein 1 NF-κB NF-κB protein Oral administration Pretreatment Pseudoephedrine Scratching Scratching behavior Skin Skin diseases Thymic stromal lymphopoietin Transcription factors Tumor necrosis factor-α γ-Interferon
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