A Pilot Screen of a Novel Peptide Hormone Library Identified Candidate GPR83 Ligands

The identification of novel peptide hormones by functional screening is challenging because posttranslational processing is frequently required to generate biologically active hormones from inactive precursors. We developed an approach for functional screening of novel potential hormones by expressi...

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Veröffentlicht in:SLAS discovery 2020-10, Vol.25 (9), p.1047-1063
Hauptverfasser: Sallee, Nathan A., Lee, Ernestine, Leffert, Atossa, Ramirez, Silvia, Brace, Arthur D., Halenbeck, Robert, Kavanaugh, W. Michael, Sullivan, Kathleen M. C.
Format: Artikel
Sprache:eng
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