Dual‐Emissive Platinum(II) Metallacage with a Sensitive Oxygen Response for Imaging of Hypoxia and Imaging‐Guided Chemotherapy

Imaging of hypoxia in vivo helps with accurate cancer diagnosis and evaluation of therapeutic outcomes. A PtII metallacage with oxygen‐responsive red phosphorescence and steady fluorescence for in vivo hypoxia imaging and chemotherapy is reported. The therapeutic agent and diagnostic probe were inte...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Angewandte Chemie International Edition 2020-11, Vol.59 (45), p.20208-20214
Hauptverfasser:	Zhu, Huangtianzhi, Li, Qi, Shi, Bingbing, Ge, Fujing, Liu, Yuezhou, Mao, Zhengwei, Zhu, Hong, Wang, Sheng, Yu, Guocan, Huang, Feihe, Stang, Peter J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Antineoplastic Agents - therapeutic use Biomedical materials Cell Hypoxia Chemical compounds Chemotherapy Diagnostic systems Fluorescence Fluorescence Resonance Energy Transfer Humans Hypoxia hypoxia imaging Medical imaging metallacages Nanoparticles Neoplasms - diagnosis Neoplasms - drug therapy Neoplasms - metabolism Neoplasms - pathology Oxygen Oxygen - analysis Pharmacology Phosphorescence Platinum Platinum - chemistry Precision Medicine self-assembly Spectrophotometry, Ultraviolet supramolecular chemistry
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!