3D Bioprinting the Cardiac Purkinje System Using Human Adipogenic Mesenchymal Stem Cell Derived Purkinje Cells

Purpose The objective of this study was to reprogram human adipogenic mesenchymal stem cells (hADMSCs) to form Purkinje cells and to use the reprogrammed Purkinje cells to bioprint Purkinje networks. Methods hADMSCs were reprogrammed to form Purkinje cells using a multi-step process using transcript...

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Veröffentlicht in:	Cardiovascular engineering and technology 2020-10, Vol.11 (5), p.587-604
Hauptverfasser:	Tracy, Evan P., Gettler, Brian C., Zakhari, Joseph S., Schwartz, Robert J., Williams, Stuart K., Birla, Ravi K.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adipogenesis Bioengineering Biomedical Engineering and Bioengineering Biomedicine Bioprinting Cardiology Cell Communication Cells, Cultured Cellular Reprogramming Cellular Reprogramming Techniques Collagen Engineering Humans Membranes Mesenchymal Stem Cells - physiology Networks Optimization Original Article Phenotype Printing, Three-Dimensional Proteins Purkinje Fibers - cytology Purkinje Fibers - physiology Stem cells Three dimensional printing Transcription Factors - genetics Transcription Factors - metabolism Transcription, Genetic
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