Use of a Hyperosmolar Saline Solution to Mitigate Proinflammatory and Degradative Responses of Articular Cartilage and Meniscus for Application to Arthroscopic Surgery

This study was designed to evaluate differences in proinflammatory and degradative mediator production and extracellular matrix degradation from osteoarthritic knee articular cartilage and meniscus explants treated with either hyperosmolar saline or isotonic saline. 6 mm-diameter full-thickness expl...

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Veröffentlicht in:	Arthroscopy 2020-12, Vol.36 (12), p.3050-3057
Hauptverfasser:	Oladeji, Lasun O., Stoker, Aaron M., Stannard, James P., Cook, James L.
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Arthroplasty, Replacement, Knee Arthroscopy Cartilage, Articular - pathology Cartilage, Articular - surgery Female Glycosaminoglycans - analysis Humans Inflammation - therapy Knee Joint - surgery Male Matrix Metalloproteinase 2 - analysis Meniscus - pathology Meniscus - surgery Osmolar Concentration Saline Solution - therapeutic use
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