Specific macrophage subsets accumulate in human subcutaneous and omental fat depots during obesity

Obesity is a chronic inflammatory disease associated with adipose tissue macrophage (ATM) activation. ATMs from lean mice contribute to tissue homeostasis by their M2‐oriented polarization, whereas obesity leads to an increase of M1 inflammatory ATMs that underlies obesity‐related metabolic disorder...

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Veröffentlicht in:Immunology and cell biology 2020-11, Vol.98 (10), p.868-882
Hauptverfasser: Girón‐Ulloa, Angélica, González‐Domínguez, Erika, Klimek, Rebeca S, Patiño‐Martínez, Eduardo, Vargas‐Ayala, Germán, Segovia‐Gamboa, Norma C, Campos‐Peña, Victoria, Rodríguez‐Arellano, Martha E, Meraz‐Ríos, Marco A, Campos‐Campos, Salvador F, Sánchez‐Torres, Carmen
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