Loss‐of‐function mutation in DNAH8 induces asthenoteratospermia associated with multiple morphological abnormalities of the sperm flagella

Asthenozoospermia is a common cause of male infertility associated with the reduced motility and/or abnormal morphology of spermatozoa, although its etiology remains incompletely understood. Multiple morphological abnormalities of the sperm flagella (MMAF) is one of the main causes of asthenozoosper...

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Veröffentlicht in:	Clinical genetics 2020-10, Vol.98 (4), p.396-401
Hauptverfasser:	Yang, Yihong, Jiang, Chuan, Zhang, Xueguang, Liu, Xue, Li, Jinghong, Qiao, Xiaoyong, Liu, Hongqian, Shen, Ying
Format:	Artikel
Sprache:	eng
Schlagworte:	asthenozoospermia DNAH8 Etiology Flagella gene mutations Immunofluorescence Infertility male infertility MMAF Morphology Mutation Sperm WES Western blotting
Online-Zugang:	Volltext
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