Mentalization and depressive symptoms in a clinical sample of adolescents and young adults
Background Increasing evidence supports that mentalization deficits may have a role in the genesis of young age depression; however, few studies examined this issue in clinical populations. Methods Outpatients aged 14–21, suffering from various psychiatric disorders, were assessed using the Mentaliz...
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| Veröffentlicht in: | Child and adolescent mental health 2017-05, Vol.22 (2), p.69-76 |
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| container_title | Child and adolescent mental health |
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| creator | Belvederi Murri, Martino Ferrigno, Gabriella Penati, Simona Muzio, Caterina Piccinini, Giulia Innamorati, Marco Ricci, Federica Pompili, Maurizio Amore, Mario |
| description | Background
Increasing evidence supports that mentalization deficits may have a role in the genesis of young age depression; however, few studies examined this issue in clinical populations.
Methods
Outpatients aged 14–21, suffering from various psychiatric disorders, were assessed using the Mentalization Questionnaire (MZQ), the Beck Depression Inventory (BDI), and the Childhood Trauma Questionnaire (CTQ), using data from age‐matched healthy students for comparison. The relationship between CTQ, MZQ, and BDI scores was examined at the cross‐sectional level, including mediation analyses, and longitudinally, in a subsample who underwent a psychotherapy intervention.
Results
Of 83 subjects, 33 (39.8%) had mentalization levels that were 1 standard deviation below those of comparison subjects. In the whole sample, the levels of mentalization were inversely associated with BDI (r = −.68, p |
| doi_str_mv | 10.1111/camh.12195 |
| format | Article |
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Increasing evidence supports that mentalization deficits may have a role in the genesis of young age depression; however, few studies examined this issue in clinical populations.
Methods
Outpatients aged 14–21, suffering from various psychiatric disorders, were assessed using the Mentalization Questionnaire (MZQ), the Beck Depression Inventory (BDI), and the Childhood Trauma Questionnaire (CTQ), using data from age‐matched healthy students for comparison. The relationship between CTQ, MZQ, and BDI scores was examined at the cross‐sectional level, including mediation analyses, and longitudinally, in a subsample who underwent a psychotherapy intervention.
Results
Of 83 subjects, 33 (39.8%) had mentalization levels that were 1 standard deviation below those of comparison subjects. In the whole sample, the levels of mentalization were inversely associated with BDI (r = −.68, p < .001) and CTQ scores (r = −.30, p = .006). Moreover, MZQ scores mediated a large part of the effect of childhood trauma on depression (total effect: 10.6, 95% CI: 5.3, 15.9; direct effect: 6.5, 95% CI: 2.1, 10.8; indirect effect: 4.1, 95% CI: 1.5, 7.4). This effect was almost entirely explained by the Affect Regulation subscale. In patients re‐evaluated after four sessions (n = 37), the decrease in BDI scores correlated with the increase in MZQ scores (r = .40, p = .02).
Conclusions
In a juvenile clinical sample, deficits of mentalization abilities were associated with the severity of depression and explained part of the depressogenic effects of childhood trauma.</description><identifier>ISSN: 1475-357X</identifier><identifier>EISSN: 1475-3588</identifier><identifier>DOI: 10.1111/camh.12195</identifier><language>eng</language><publisher>London: Wiley Subscription Services, Inc</publisher><subject>Adolescent ; anxiety ; childhood trauma ; depression ; mentalization ; psychotherapy</subject><ispartof>Child and adolescent mental health, 2017-05, Vol.22 (2), p.69-76</ispartof><rights>2016 Association for Child and Adolescent Mental Health</rights><rights>Copyright © 2017 Association for Child and Adolescent Mental Health</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c3345-d6abcc6b331a80eb07309935c0385ef0643788984c866afd8f16d08338505e5d3</citedby><cites>FETCH-LOGICAL-c3345-d6abcc6b331a80eb07309935c0385ef0643788984c866afd8f16d08338505e5d3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1111%2Fcamh.12195$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1111%2Fcamh.12195$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>314,780,784,1417,27923,27924,45573,45574</link.rule.ids></links><search><creatorcontrib>Belvederi Murri, Martino</creatorcontrib><creatorcontrib>Ferrigno, Gabriella</creatorcontrib><creatorcontrib>Penati, Simona</creatorcontrib><creatorcontrib>Muzio, Caterina</creatorcontrib><creatorcontrib>Piccinini, Giulia</creatorcontrib><creatorcontrib>Innamorati, Marco</creatorcontrib><creatorcontrib>Ricci, Federica</creatorcontrib><creatorcontrib>Pompili, Maurizio</creatorcontrib><creatorcontrib>Amore, Mario</creatorcontrib><title>Mentalization and depressive symptoms in a clinical sample of adolescents and young adults</title><title>Child and adolescent mental health</title><description>Background
Increasing evidence supports that mentalization deficits may have a role in the genesis of young age depression; however, few studies examined this issue in clinical populations.
Methods
Outpatients aged 14–21, suffering from various psychiatric disorders, were assessed using the Mentalization Questionnaire (MZQ), the Beck Depression Inventory (BDI), and the Childhood Trauma Questionnaire (CTQ), using data from age‐matched healthy students for comparison. The relationship between CTQ, MZQ, and BDI scores was examined at the cross‐sectional level, including mediation analyses, and longitudinally, in a subsample who underwent a psychotherapy intervention.
Results
Of 83 subjects, 33 (39.8%) had mentalization levels that were 1 standard deviation below those of comparison subjects. In the whole sample, the levels of mentalization were inversely associated with BDI (r = −.68, p < .001) and CTQ scores (r = −.30, p = .006). Moreover, MZQ scores mediated a large part of the effect of childhood trauma on depression (total effect: 10.6, 95% CI: 5.3, 15.9; direct effect: 6.5, 95% CI: 2.1, 10.8; indirect effect: 4.1, 95% CI: 1.5, 7.4). This effect was almost entirely explained by the Affect Regulation subscale. In patients re‐evaluated after four sessions (n = 37), the decrease in BDI scores correlated with the increase in MZQ scores (r = .40, p = .02).
Conclusions
In a juvenile clinical sample, deficits of mentalization abilities were associated with the severity of depression and explained part of the depressogenic effects of childhood trauma.</description><subject>Adolescent</subject><subject>anxiety</subject><subject>childhood trauma</subject><subject>depression</subject><subject>mentalization</subject><subject>psychotherapy</subject><issn>1475-357X</issn><issn>1475-3588</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2017</creationdate><recordtype>article</recordtype><recordid>eNp9kEFLxDAQhYMouK5e_AUBLyJ0TZomTY_Loq6wixcF8RKyaapZ0qQ2rVJ_vdmtePDgXGaY-d5jeACcYzTDsa6VrN9mOMUFPQATnOU0IZTzw985fz4GJyFsEcI5ydgEvKy166Q1X7Iz3kHpSljqptUhmA8Nw1A3na8DNPEElTXOKGlhkHVjNfQVlKW3OqjoEfbawffuNW5724VTcFRJG_TZT5-Cp9ubx8UyWT3c3S_mq0QRktGkZHKjFNsQgiVHeoNygoqCUIUIp7pCLCM55wXPFGdMViWvMCsRJ_GKqKYlmYLL0bdp_XuvQydqE1-yVjrt-yDSLM2KIs1JHtGLP-jW962L3wnMOWcIccwidTVSqvUhtLoSTWtq2Q4CI7GLWexiFvuYI4xH-NNYPfxDisV8vRw131P9fx4</recordid><startdate>201705</startdate><enddate>201705</enddate><creator>Belvederi Murri, Martino</creator><creator>Ferrigno, Gabriella</creator><creator>Penati, Simona</creator><creator>Muzio, Caterina</creator><creator>Piccinini, Giulia</creator><creator>Innamorati, Marco</creator><creator>Ricci, Federica</creator><creator>Pompili, Maurizio</creator><creator>Amore, Mario</creator><general>Wiley Subscription Services, Inc</general><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>201705</creationdate><title>Mentalization and depressive symptoms in a clinical sample of adolescents and young adults</title><author>Belvederi Murri, Martino ; Ferrigno, Gabriella ; Penati, Simona ; Muzio, Caterina ; Piccinini, Giulia ; Innamorati, Marco ; Ricci, Federica ; Pompili, Maurizio ; Amore, Mario</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c3345-d6abcc6b331a80eb07309935c0385ef0643788984c866afd8f16d08338505e5d3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2017</creationdate><topic>Adolescent</topic><topic>anxiety</topic><topic>childhood trauma</topic><topic>depression</topic><topic>mentalization</topic><topic>psychotherapy</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Belvederi Murri, Martino</creatorcontrib><creatorcontrib>Ferrigno, Gabriella</creatorcontrib><creatorcontrib>Penati, Simona</creatorcontrib><creatorcontrib>Muzio, Caterina</creatorcontrib><creatorcontrib>Piccinini, Giulia</creatorcontrib><creatorcontrib>Innamorati, Marco</creatorcontrib><creatorcontrib>Ricci, Federica</creatorcontrib><creatorcontrib>Pompili, Maurizio</creatorcontrib><creatorcontrib>Amore, Mario</creatorcontrib><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Child and adolescent mental health</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Belvederi Murri, Martino</au><au>Ferrigno, Gabriella</au><au>Penati, Simona</au><au>Muzio, Caterina</au><au>Piccinini, Giulia</au><au>Innamorati, Marco</au><au>Ricci, Federica</au><au>Pompili, Maurizio</au><au>Amore, Mario</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Mentalization and depressive symptoms in a clinical sample of adolescents and young adults</atitle><jtitle>Child and adolescent mental health</jtitle><date>2017-05</date><risdate>2017</risdate><volume>22</volume><issue>2</issue><spage>69</spage><epage>76</epage><pages>69-76</pages><issn>1475-357X</issn><eissn>1475-3588</eissn><abstract>Background
Increasing evidence supports that mentalization deficits may have a role in the genesis of young age depression; however, few studies examined this issue in clinical populations.
Methods
Outpatients aged 14–21, suffering from various psychiatric disorders, were assessed using the Mentalization Questionnaire (MZQ), the Beck Depression Inventory (BDI), and the Childhood Trauma Questionnaire (CTQ), using data from age‐matched healthy students for comparison. The relationship between CTQ, MZQ, and BDI scores was examined at the cross‐sectional level, including mediation analyses, and longitudinally, in a subsample who underwent a psychotherapy intervention.
Results
Of 83 subjects, 33 (39.8%) had mentalization levels that were 1 standard deviation below those of comparison subjects. In the whole sample, the levels of mentalization were inversely associated with BDI (r = −.68, p < .001) and CTQ scores (r = −.30, p = .006). Moreover, MZQ scores mediated a large part of the effect of childhood trauma on depression (total effect: 10.6, 95% CI: 5.3, 15.9; direct effect: 6.5, 95% CI: 2.1, 10.8; indirect effect: 4.1, 95% CI: 1.5, 7.4). This effect was almost entirely explained by the Affect Regulation subscale. In patients re‐evaluated after four sessions (n = 37), the decrease in BDI scores correlated with the increase in MZQ scores (r = .40, p = .02).
Conclusions
In a juvenile clinical sample, deficits of mentalization abilities were associated with the severity of depression and explained part of the depressogenic effects of childhood trauma.</abstract><cop>London</cop><pub>Wiley Subscription Services, Inc</pub><doi>10.1111/camh.12195</doi><tpages>8</tpages></addata></record> |
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| source | Wiley Online Library Journals Frontfile Complete |
| subjects | Adolescent anxiety childhood trauma depression mentalization psychotherapy |
| title | Mentalization and depressive symptoms in a clinical sample of adolescents and young adults |
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