Screening of plant derived chalcones on the inhibition of potato apyrase: Potential protein biotechnological applications in health

NTPDases (EC 3.6.1.5) are enzymes belonging to a protein family which have as a common feature the ability to hydrolyze di- and triphosphate nucleotides (ADP and ATP) to monophosphate nucleosides (AMP) in the presence of Ca+2 and Mg+. The potato apyrase has been the first protein of the NTPDase fami...

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Veröffentlicht in:	International journal of biological macromolecules 2020-12, Vol.164, p.687-693
Hauptverfasser:	Farani, Priscila Silva Grijó, Marconato, Danielle Gomes, Emídio, Nayara Braga, Pereira, Vinícius R.D., Alves Junior, Ismael J., da Silveira, Lígia S., Couri, Mara R.C., Vasconcelos, Eveline Gomes, Castro-Borges, William, Filho, Ademar Alves Silva, Faria-Pinto, Priscila
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenosine Triphosphate - chemistry Adenosine Triphosphate - genetics Amino Acid Sequence - genetics Antigens, CD - chemistry Antigens, CD - genetics Apyrase - antagonists & inhibitors Apyrase - chemistry Apyrase - genetics Biotechnology Chalcones Chalcones - chemistry Chalcones - pharmacology Chromatography, Liquid Enzyme inhibition Humans Hydrolysis - drug effects NTPDase Protein Engineering Solanum tuberosum Solanum tuberosum - enzymology Tandem Mass Spectrometry
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