Analogs of the Cathelicidin-Derived Antimicrobial Peptide PMAP-23 Exhibit Improved Stability and Antibacterial Activity

Antimicrobial peptides (AMPs) have gained interesting as a new type of antimicrobial agent. The cathelicidin-derived antimicrobial peptide PMAP-23 has broad-spectrum antibacterial activity, and to improve its antimicrobial activity, we used amino acid substitution at position 5 or 19 of PMAP-23 to d...

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Veröffentlicht in:	Probiotics and antimicrobial proteins 2021-02, Vol.13 (1), p.273-286
Hauptverfasser:	Liu, Yongqing, Shen, Tengfei, Chen, Liangliang, Zhou, Jiangfei, Wang, Chen
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino acid substitution Antibacterial activity Antimicrobial activity Antimicrobial agents Antimicrobial peptides Applied Microbiology Chemistry Chemistry and Materials Science Chemistry/Food Science Cytotoxicity Microbiology Nutrition Peptides Protein Science
Online-Zugang:	Volltext
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