Low-Dose Testosterone Augmentation for Antidepressant-Resistant Major Depressive Disorder in Women: An 8-Week Randomized Placebo-Controlled Study

Objective:Low-dose testosterone has been shown to improve depression symptom severity, fatigue, and sexual function in small studies in women not formally diagnosed with major depressive disorder. The authors sought to determine whether adjunctive low-dose transdermal testosterone improves depressio...

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Veröffentlicht in:	The American journal of psychiatry 2020-10, Vol.177 (10), p.965-973
Hauptverfasser:	Dichtel, Laura E, Carpenter, Linda L, Nyer, Maren, Mischoulon, David, Kimball, Allison, Deckersbach, Thilo, Dougherty, Darin D, Schoenfeld, David A, Fisher, Lauren, Cusin, Cristina, Dording, Christina, Trinh, Nhi-Ha, Pedrelli, Paola, Yeung, Albert, Farabaugh, Amy, Papakostas, George I, Chang, Trina, Shapero, Benjamin G, Chen, Justin, Cassano, Paolo, Hahn, Emily M, Rao, Elizabeth M, Brady, Roscoe O, Singh, Ravinder J, Tyrka, Audrey R, Price, Lawrence H, Fava, Maurizio, Miller, Karen K
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Antidepressants Depressive Disorder, Major - diagnostic imaging Depressive Disorder, Major - drug therapy Depressive Disorder, Treatment-Resistant - diagnostic imaging Depressive Disorder, Treatment-Resistant - drug therapy Double-Blind Method Drug Therapy, Combination Female Functional Neuroimaging Gyrus Cinguli - diagnostic imaging Humans Hydrocortisone - blood Magnetic Resonance Imaging Mental depression Middle Aged Placebo effect Skin Cream Testosterone Testosterone - administration & dosage Testosterone - blood Testosterone - therapeutic use Young Adult
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