Seasonal Variations in Macrophages/Microglia Underlie Changes in the Mouse Model of Multiple Sclerosis Severity

Both immune and neurodegenerative mechanisms underlie multiple sclerosis (MS) and its animal model, experimental autoimmune encephalomyelitis (EAE). MS/EAE are triggered by encephalitogenic immune cells, including Th1 and Th17 cells, whereas T regulatory (Treg) cells are involved in inflammation res...

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Veröffentlicht in:	Molecular neurobiology 2020-10, Vol.57 (10), p.4082-4089
Hauptverfasser:	Álvarez-Sánchez, Nuria, Cruz-Chamorro, Ivan, Álvarez-López, Ana I., López-González, Antonio, Lacalle Remigio, Juan Ramón, Lardone, Patricia J., Guerrero, Juan M., Martínez-López, Alicia, Carrillo-Vico, Antonio
Format:	Artikel
Sprache:	eng
Schlagworte:	Animal models Biomedical and Life Sciences Biomedicine Cell Biology Central nervous system Controlled conditions Environmental factors Experimental allergic encephalomyelitis Helper cells Immune response Inflammation Lymphocytes T Macrophages Microglia Multiple sclerosis Myelin Neurobiology Neurology Neurosciences Oligodendrocyte-myelin glycoprotein Original Article Perinatal exposure Seasonal variations Summer
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