Autophagy in diabetic nephropathy: a review

Diabetes mellitus (DM) is the leading cause of end stage renal disease. 40% of the patients worldwide will require replacement therapy after 20 years of DM worldwide. Early-stage diabetic nephropathy is characterized by hyperfiltration related to hypeglycemia-induced afferent artery vasodilatation w...

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Veröffentlicht in:	International urology and nephrology 2020-09, Vol.52 (9), p.1705-1712
Hauptverfasser:	Koch, Elias A. T., Nakhoul, Rola, Nakhoul, Farid, Nakhoul, Nakhoul
Format:	Artikel
Sprache:	eng
Schlagworte:	Aldosterone Angiotensin Autophagy Autophagy - physiology Carbohydrate metabolism Cardiovascular disease Clear cell-type renal cell carcinoma Coronary artery Diabetes Diabetes mellitus Diabetic Nephropathies - complications Diabetic Nephropathies - physiopathology Diabetic nephropathy Diabetic retinopathy Endothelial cells Epithelial cells Gene expression Glomerular filtration rate Haptoglobin Heart diseases Humans Inflammation Interleukins Kidney diseases Klotho protein Medicine Medicine & Public Health Nephrology Nephrology - Review Nephropathy Phagocytosis Phenotypes Protein turnover Proteinuria Sensory neurons Urology Vascular diseases Vasodilation Vitamin D
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