Development of anti-human CADM1 monoclonal antibodies as a potential therapy for adult T-cell leukemia/lymphoma

Adult T-cell leukemia/lymphoma (ATLL) is a highly invasive and refractory T-cell malignancy, with poor prognosis. We previously identified that cell adhesion molecule 1 (CADM1) is overexpressed consistently in ATLL cells, and that CADM1 expression increases the adhesion capacity of ATLL cells to end...

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Veröffentlicht in:International journal of hematology 2020-10, Vol.112 (4), p.496-503
Hauptverfasser: Chilmi, Syahrul, Nakahata, Shingo, Fauzi, Yanuar Rahmat, Ichikawa, Tomonaga, Tani, Chikako, Suwanruengsri, Mathurot, Yamaguchi, Ryoji, Matsuura, Tadashi, Kurosawa, Gene, Morishita, Kazuhiro
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Sprache:eng
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