Insulin-like growth factor-I rescue of primary keratinocytes from pre- and post-ultraviolet B radiation effects

Ultraviolet B radiation (UVBR) induces the formation of photolesions in epidermal keratinocytes, potentially affecting cellular function and contributing towards malignant transformation. Insulin-like growth factor-I (IGF-I) contributes to protection of keratinocytes against UVBR-induced damage. Stu...

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Veröffentlicht in:	Journal of photochemistry and photobiology. B, Biology Biology, 2020-08, Vol.209, p.111951-111951, Article 111951
Hauptverfasser:	Andrade, Melisa J., Satyamoorthy, Kapaettu, Upton, Zee, Van Lonkhuyzen, Derek R.
Format:	Artikel
Sprache:	eng
Schlagworte:	Apoptosis Cell cycle Cell survival Damage prevention DNA damage Growth factors Insulin Insulin-like growth factor Insulin-like growth factor I Insulin-like growth factors Keratinocyte Keratinocytes Photobiology Radiation effects Signalling pathways Skin Skin models Survival Three dimensional models Two dimensional models Ultraviolet radiation
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