Macrophage polarization and its role in the pathogenesis of acute lung injury/acute respiratory distress syndrome

Purpose Macrophages are highly plastic cells. Under different stimuli, macrophages can be polarized into several different subsets. Two main macrophage subsets have been suggested: classically activated or inflammatory (M1) macrophages and alternatively activated or anti-inflammatory (M2) macrophage...

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Veröffentlicht in:	Inflammation research 2020-09, Vol.69 (9), p.883-895
Hauptverfasser:	Chen, Xuxin, Tang, Jian, Shuai, Weizheng, Meng, Jiguang, Feng, Jian, Han, Zhihai
Format:	Artikel
Sprache:	eng
Schlagworte:	Acute Lung Injury - etiology Allergology Biomedical and Life Sciences Biomedicine Cell Biology Cell Polarity Dermatology Humans Immunology Inflammation JNK Mitogen-Activated Protein Kinases - physiology Life Sciences & Biomedicine Literature reviews Lungs Macrophages Macrophages - physiology Neurology NF-kappa B - physiology Pathogenesis Pharmacology/Toxicology Polarization Regulation Regulatory mechanisms (biology) Respiratory distress syndrome Respiratory Distress Syndrome - etiology Review Rheumatology Science & Technology Signal Transduction - physiology Therapeutic applications Transforming Growth Factor beta - physiology
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