Pannexin 1 Channels as a Therapeutic Target: Structure, Inhibition, and Outlook

Pannexin 1 (Panx1) channels are transmembrane proteins that release adenosine triphosphate and play an important role in intercellular communication. They are widely expressed in somatic and nervous system tissues, and their activity has been associated with many pathologies such as stroke, epilepsy...

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Veröffentlicht in:	ACS chemical neuroscience 2020-08, Vol.11 (15), p.2163-2172
Hauptverfasser:	Navis, Kathleen E, Fan, Churmy Y, Trang, Tuan, Thompson, Roger J, Derksen, Darren J
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenosine Triphosphate Connexins Epilepsy Humans Nerve Tissue Proteins
Online-Zugang:	Volltext
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