Enhanced oxidative stress and damage in glycated erythrocytes

Diabetes is associated with a dramatic mortality rate due to its vascular complications. Chronic hyperglycemia in diabetes leads to enhanced glycation of erythrocytes and oxidative stress. Even though erythrocytes play a determining role in vascular complications, very little is known about how eryt...

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Veröffentlicht in:	PloS one 2020-07, Vol.15 (7), p.e0235335-e0235335, Article 0235335
Hauptverfasser:	Turpin, Chloe, Catan, Aurelie, Guerin-Dubourg, Alexis, Debussche, Xavier, Bravo, Susana B., Alvarez, Ezequiel, Van den Elsen, Jean, Meilhac, Olivier, Rondeau, Philippe, Bourdon, Emmanuel
Format:	Artikel
Sprache:	eng
Schlagworte:	Antioxidants Biology and Life Sciences Blood Blood cells Cardiology and cardiovascular system Cardiovascular disease Cellular Biology Complications Damage accumulation Damage detection Deformability Diabetes Diabetes mellitus Diabetes research Endothelial cells Enzymatic activity Erythrocytes Formability Glucose Glycosylation Health aspects Hematology Hemoglobin Human health and pathology Hyperglycemia Impact damage Incubation Life Sciences Medicine and Health Sciences Mortality Multidisciplinary Sciences Oxidative stress Oxygen Phagocytosis Phosphatidylserine Physical Sciences Proteins Reactive oxygen species Red blood cells Science & Technology Science & Technology - Other Topics Structure
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