The presence of odd-chain fatty acids in Drosophila phospholipids
Most fatty acids in phospholipids and other lipid species carry an even number of carbon atoms. Also odd-chain fatty acids (OCFAs), such as C15:0 and C17:0, are widespread throughout the living organism. However, the qualitative and quantitative profiles of OCFAs-containing lipids in living organism...
Gespeichert in:
| Veröffentlicht in: | Bioscience, biotechnology, and biochemistry biotechnology, and biochemistry, 2020-10, Vol.84 (10), p.2139-2148 |
|---|---|
| Hauptverfasser: | , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 2148 |
|---|---|
| container_issue | 10 |
| container_start_page | 2139 |
| container_title | Bioscience, biotechnology, and biochemistry |
| container_volume | 84 |
| creator | Sato, Ayaka Ohhara, Yuya Miura, Shinji Yamakawa-Kobayashi, Kimiko |
| description | Most fatty acids in phospholipids and other lipid species carry an even number of carbon atoms. Also odd-chain fatty acids (OCFAs), such as C15:0 and C17:0, are widespread throughout the living organism. However, the qualitative and quantitative profiles of OCFAs-containing lipids in living organisms remain unclear. Here, we show that OCFAs are present in Drosophila phosphatidylcholine (PC) and phosphatidylethanolamine (PE) and that their level increases in accordance with progression of growth. Furthermore, we found that food-derived propionic acid/propanoic acid (C3:0) is utilized for production of OCFA-containing PC and PE. This study provides the basis for understanding in vivo function of OCFA-containing phospholipids in development and lipid homeostasis.
Food-derived propionic acid is utilized for production of OCFA-containing phosphatidylcholine (PC) and phosphatidylethanolamine (PE) in Drosophila. |
| doi_str_mv | 10.1080/09168451.2020.1790337 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_2421111394</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><oup_id>10.1080/09168451.2020.1790337</oup_id><sourcerecordid>2421111394</sourcerecordid><originalsourceid>FETCH-LOGICAL-c431t-d6147920df4554cd7decea7587b1a9de0df7adaa3963f1b882f77403e5658e843</originalsourceid><addsrcrecordid>eNqNkF1LwzAUhoMobk5_gtJLbzqTJmnaO8fmFwy8mdchyweNtE1NWmT_3pRuXoqBQ8g5z_vm8AJwi-ASwQI-wBLlBaFomcEstlgJMWZnYI4wYWleEnYO5iOTjtAMXIXwCWFsUHQJZjjLIw3hHKx2lU46r4NupU6cSZxSqayEbRMj-v6QCGlVSOJz411wXWVrkXSVC7Fq28XZNbgwog765ngvwMfz0279mm7fX97Wq20qCUZ9qnJEWJlBZQilRCqmtNSC0YLtkSiVjgMmlBC4zLFB-6LIDGMEYk1zWuiC4AW4n3w7774GHXre2CB1XYtWuyHwjGQoHlyOKJ1QGXcOXhveedsIf-AI8jE9fkqPj-nxY3pRd3f8Ytg3Wv2qTnFFAE6AG7p_ez5OEtsa5xvx7XyteC8OtfPGi1bawPHfFj_Fq4ta</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2421111394</pqid></control><display><type>article</type><title>The presence of odd-chain fatty acids in Drosophila phospholipids</title><source>Oxford University Press Journals All Titles (1996-Current)</source><source>MEDLINE</source><source>Freely Accessible Japanese Titles</source><source>EZB-FREE-00999 freely available EZB journals</source><creator>Sato, Ayaka ; Ohhara, Yuya ; Miura, Shinji ; Yamakawa-Kobayashi, Kimiko</creator><creatorcontrib>Sato, Ayaka ; Ohhara, Yuya ; Miura, Shinji ; Yamakawa-Kobayashi, Kimiko</creatorcontrib><description>Most fatty acids in phospholipids and other lipid species carry an even number of carbon atoms. Also odd-chain fatty acids (OCFAs), such as C15:0 and C17:0, are widespread throughout the living organism. However, the qualitative and quantitative profiles of OCFAs-containing lipids in living organisms remain unclear. Here, we show that OCFAs are present in Drosophila phosphatidylcholine (PC) and phosphatidylethanolamine (PE) and that their level increases in accordance with progression of growth. Furthermore, we found that food-derived propionic acid/propanoic acid (C3:0) is utilized for production of OCFA-containing PC and PE. This study provides the basis for understanding in vivo function of OCFA-containing phospholipids in development and lipid homeostasis.
Food-derived propionic acid is utilized for production of OCFA-containing phosphatidylcholine (PC) and phosphatidylethanolamine (PE) in Drosophila.</description><identifier>ISSN: 0916-8451</identifier><identifier>EISSN: 1347-6947</identifier><identifier>DOI: 10.1080/09168451.2020.1790337</identifier><identifier>PMID: 32633700</identifier><language>eng</language><publisher>England: Taylor & Francis</publisher><subject>Animals ; Drosophila ; Drosophila - chemistry ; Drosophila - metabolism ; Fatty Acids - biosynthesis ; Fatty Acids - chemistry ; Odd-chain fatty acid ; phospholipid ; Phospholipids - chemistry ; Propionates - metabolism ; propionic acid</subject><ispartof>Bioscience, biotechnology, and biochemistry, 2020-10, Vol.84 (10), p.2139-2148</ispartof><rights>2020 Japan Society for Bioscience, Biotechnology, and Agrochemistry 2020</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c431t-d6147920df4554cd7decea7587b1a9de0df7adaa3963f1b882f77403e5658e843</citedby><cites>FETCH-LOGICAL-c431t-d6147920df4554cd7decea7587b1a9de0df7adaa3963f1b882f77403e5658e843</cites><orcidid>0000-0001-8806-9763 ; 0000-0002-4351-8665</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27901,27902</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/32633700$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Sato, Ayaka</creatorcontrib><creatorcontrib>Ohhara, Yuya</creatorcontrib><creatorcontrib>Miura, Shinji</creatorcontrib><creatorcontrib>Yamakawa-Kobayashi, Kimiko</creatorcontrib><title>The presence of odd-chain fatty acids in Drosophila phospholipids</title><title>Bioscience, biotechnology, and biochemistry</title><addtitle>Biosci Biotechnol Biochem</addtitle><description>Most fatty acids in phospholipids and other lipid species carry an even number of carbon atoms. Also odd-chain fatty acids (OCFAs), such as C15:0 and C17:0, are widespread throughout the living organism. However, the qualitative and quantitative profiles of OCFAs-containing lipids in living organisms remain unclear. Here, we show that OCFAs are present in Drosophila phosphatidylcholine (PC) and phosphatidylethanolamine (PE) and that their level increases in accordance with progression of growth. Furthermore, we found that food-derived propionic acid/propanoic acid (C3:0) is utilized for production of OCFA-containing PC and PE. This study provides the basis for understanding in vivo function of OCFA-containing phospholipids in development and lipid homeostasis.
Food-derived propionic acid is utilized for production of OCFA-containing phosphatidylcholine (PC) and phosphatidylethanolamine (PE) in Drosophila.</description><subject>Animals</subject><subject>Drosophila</subject><subject>Drosophila - chemistry</subject><subject>Drosophila - metabolism</subject><subject>Fatty Acids - biosynthesis</subject><subject>Fatty Acids - chemistry</subject><subject>Odd-chain fatty acid</subject><subject>phospholipid</subject><subject>Phospholipids - chemistry</subject><subject>Propionates - metabolism</subject><subject>propionic acid</subject><issn>0916-8451</issn><issn>1347-6947</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2020</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqNkF1LwzAUhoMobk5_gtJLbzqTJmnaO8fmFwy8mdchyweNtE1NWmT_3pRuXoqBQ8g5z_vm8AJwi-ASwQI-wBLlBaFomcEstlgJMWZnYI4wYWleEnYO5iOTjtAMXIXwCWFsUHQJZjjLIw3hHKx2lU46r4NupU6cSZxSqayEbRMj-v6QCGlVSOJz411wXWVrkXSVC7Fq28XZNbgwog765ngvwMfz0279mm7fX97Wq20qCUZ9qnJEWJlBZQilRCqmtNSC0YLtkSiVjgMmlBC4zLFB-6LIDGMEYk1zWuiC4AW4n3w7774GHXre2CB1XYtWuyHwjGQoHlyOKJ1QGXcOXhveedsIf-AI8jE9fkqPj-nxY3pRd3f8Ytg3Wv2qTnFFAE6AG7p_ez5OEtsa5xvx7XyteC8OtfPGi1bawPHfFj_Fq4ta</recordid><startdate>20201002</startdate><enddate>20201002</enddate><creator>Sato, Ayaka</creator><creator>Ohhara, Yuya</creator><creator>Miura, Shinji</creator><creator>Yamakawa-Kobayashi, Kimiko</creator><general>Taylor & Francis</general><general>Oxford University Press</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><orcidid>https://orcid.org/0000-0001-8806-9763</orcidid><orcidid>https://orcid.org/0000-0002-4351-8665</orcidid></search><sort><creationdate>20201002</creationdate><title>The presence of odd-chain fatty acids in Drosophila phospholipids</title><author>Sato, Ayaka ; Ohhara, Yuya ; Miura, Shinji ; Yamakawa-Kobayashi, Kimiko</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c431t-d6147920df4554cd7decea7587b1a9de0df7adaa3963f1b882f77403e5658e843</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2020</creationdate><topic>Animals</topic><topic>Drosophila</topic><topic>Drosophila - chemistry</topic><topic>Drosophila - metabolism</topic><topic>Fatty Acids - biosynthesis</topic><topic>Fatty Acids - chemistry</topic><topic>Odd-chain fatty acid</topic><topic>phospholipid</topic><topic>Phospholipids - chemistry</topic><topic>Propionates - metabolism</topic><topic>propionic acid</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Sato, Ayaka</creatorcontrib><creatorcontrib>Ohhara, Yuya</creatorcontrib><creatorcontrib>Miura, Shinji</creatorcontrib><creatorcontrib>Yamakawa-Kobayashi, Kimiko</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Bioscience, biotechnology, and biochemistry</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Sato, Ayaka</au><au>Ohhara, Yuya</au><au>Miura, Shinji</au><au>Yamakawa-Kobayashi, Kimiko</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>The presence of odd-chain fatty acids in Drosophila phospholipids</atitle><jtitle>Bioscience, biotechnology, and biochemistry</jtitle><addtitle>Biosci Biotechnol Biochem</addtitle><date>2020-10-02</date><risdate>2020</risdate><volume>84</volume><issue>10</issue><spage>2139</spage><epage>2148</epage><pages>2139-2148</pages><issn>0916-8451</issn><eissn>1347-6947</eissn><abstract>Most fatty acids in phospholipids and other lipid species carry an even number of carbon atoms. Also odd-chain fatty acids (OCFAs), such as C15:0 and C17:0, are widespread throughout the living organism. However, the qualitative and quantitative profiles of OCFAs-containing lipids in living organisms remain unclear. Here, we show that OCFAs are present in Drosophila phosphatidylcholine (PC) and phosphatidylethanolamine (PE) and that their level increases in accordance with progression of growth. Furthermore, we found that food-derived propionic acid/propanoic acid (C3:0) is utilized for production of OCFA-containing PC and PE. This study provides the basis for understanding in vivo function of OCFA-containing phospholipids in development and lipid homeostasis.
Food-derived propionic acid is utilized for production of OCFA-containing phosphatidylcholine (PC) and phosphatidylethanolamine (PE) in Drosophila.</abstract><cop>England</cop><pub>Taylor & Francis</pub><pmid>32633700</pmid><doi>10.1080/09168451.2020.1790337</doi><tpages>10</tpages><orcidid>https://orcid.org/0000-0001-8806-9763</orcidid><orcidid>https://orcid.org/0000-0002-4351-8665</orcidid></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0916-8451 |
| ispartof | Bioscience, biotechnology, and biochemistry, 2020-10, Vol.84 (10), p.2139-2148 |
| issn | 0916-8451 1347-6947 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_2421111394 |
| source | Oxford University Press Journals All Titles (1996-Current); MEDLINE; Freely Accessible Japanese Titles; EZB-FREE-00999 freely available EZB journals |
| subjects | Animals Drosophila Drosophila - chemistry Drosophila - metabolism Fatty Acids - biosynthesis Fatty Acids - chemistry Odd-chain fatty acid phospholipid Phospholipids - chemistry Propionates - metabolism propionic acid |
| title | The presence of odd-chain fatty acids in Drosophila phospholipids |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-04T20%3A21%3A01IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=The%20presence%20of%20odd-chain%20fatty%20acids%20in%20Drosophila%20phospholipids&rft.jtitle=Bioscience,%20biotechnology,%20and%20biochemistry&rft.au=Sato,%20Ayaka&rft.date=2020-10-02&rft.volume=84&rft.issue=10&rft.spage=2139&rft.epage=2148&rft.pages=2139-2148&rft.issn=0916-8451&rft.eissn=1347-6947&rft_id=info:doi/10.1080/09168451.2020.1790337&rft_dat=%3Cproquest_cross%3E2421111394%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=2421111394&rft_id=info:pmid/32633700&rft_oup_id=10.1080/09168451.2020.1790337&rfr_iscdi=true |