Relationship between sarcopenia and orthostatic hypotension
Abstract Background The relationship between sarcopenia and orthostatic hypotension (OH) is unclear. Objectives The aim of the present study was to investigate associations between sarcopenia/sarcopenia severity and OH. Design A total of 511 patients attending a geriatric outpatient clinic were incl...
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| Veröffentlicht in: | Age and ageing 2020-11, Vol.49 (6), p.959-965 |
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| creator | Soysal, Pinar Kocyigit, Suleyman Emre Dokuzlar, Ozge Ates Bulut, Esra Smith, Lee Isik, Ahmet Turan |
| description | Abstract
Background
The relationship between sarcopenia and orthostatic hypotension (OH) is unclear.
Objectives
The aim of the present study was to investigate associations between sarcopenia/sarcopenia severity and OH.
Design
A total of 511 patients attending a geriatric outpatient clinic were included. OH was defined as a decrease in systolic and/or diastolic blood pressure of ≥ 20 mmHg and/or ≥ 10 mmHg, respectively, when one transitions from the supine to an upright position. OH was measured by the Head-up Tilt Table test at 1, 3 and 5 min (OH1, OH3 and OH5, respectively). Sarcopenia and its severity were defined according to the revised European consensus on definition and diagnosis.
Results
The mean age of the sample was 75.40 ± 7.35 years, and 69.9% were female. The prevalence of probable sarcopenia, sarcopenia and severe sarcopenia was 42.2%, 6.06% and 11.1%, respectively. After adjustment for all covariates, systolic OH1, OH1 and systolic OH5 were statistically significantly different between severe sarcopenia and the robust group (odds ratio [OR]: 3.26, confidence interval [CI] 0.98–10.84; P = 0.05 for systolic OH1; OR 4.31, CI 1.31–14.15; P = 0.016 for OH1; OR 4.09, CI 1.01–16.55; P = 0.048 for systolic OH5). Only systolic OH1 was statistically different between the sarcopenia and severe sarcopenia groups (OR 2.64, CI 1.87–8.73; P = 0.012). OH1 and OH5 were statistically significant different between severe sarcopenia and probable sarcopenia groups (P 0.05).
Conclusions
There is a close relationship between sarcopenia and severe sarcopenia and OH in older adults. Therefore, when a healthcare practitioner is evaluating an older patient with sarcopenia, OH should also be evaluated, and vice versa. |
| doi_str_mv | 10.1093/ageing/afaa077 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_2420145897</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><oup_id>10.1093/ageing/afaa077</oup_id><sourcerecordid>2420145897</sourcerecordid><originalsourceid>FETCH-LOGICAL-c440t-62b55bd6ef518acd16beb9abde86b6534f4fa3ccce76fe19ad1d3d2dd8d889903</originalsourceid><addsrcrecordid>eNqF0M9LwzAUB_AgCs7p1XPBix66JWmaJniS4S8YCKLnkiYvW0eX1KRF9t8b6U5ePD0efL6Pxxeha4IXBMtiqTbQus1SWaVwVZ2gGWFc5FQU7BTNMMY0xxWV5-gixl1aSUnoDN2_Q6eG1ru4bfusgeEbwGVRBe17cK3KlDOZD8PWxyE5nW0PvR_AxRS5RGdWdRGujnOOPp8eP1Yv-frt-XX1sM41Y3jIOW3KsjEcbEmE0obwBhqpGgOCN7wsmGVWFVprqLgFIpUhpjDUGGGEkBIXc3Q73e2D_xohDvW-jRq6TjnwY6wpo5iwUsgq0Zs_dOfH4NJ3SVWcECopTWoxKR18jAFs3Yd2r8KhJrj-7bKeuqyPXabA3RTwY_-f_QFv-Xjx</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2476112922</pqid></control><display><type>article</type><title>Relationship between sarcopenia and orthostatic hypotension</title><source>Applied Social Sciences Index & Abstracts (ASSIA)</source><source>EZB-FREE-00999 freely available EZB journals</source><source>Alma/SFX Local Collection</source><source>Oxford Journals</source><creator>Soysal, Pinar ; Kocyigit, Suleyman Emre ; Dokuzlar, Ozge ; Ates Bulut, Esra ; Smith, Lee ; Isik, Ahmet Turan</creator><creatorcontrib>Soysal, Pinar ; Kocyigit, Suleyman Emre ; Dokuzlar, Ozge ; Ates Bulut, Esra ; Smith, Lee ; Isik, Ahmet Turan</creatorcontrib><description>Abstract
Background
The relationship between sarcopenia and orthostatic hypotension (OH) is unclear.
Objectives
The aim of the present study was to investigate associations between sarcopenia/sarcopenia severity and OH.
Design
A total of 511 patients attending a geriatric outpatient clinic were included. OH was defined as a decrease in systolic and/or diastolic blood pressure of ≥ 20 mmHg and/or ≥ 10 mmHg, respectively, when one transitions from the supine to an upright position. OH was measured by the Head-up Tilt Table test at 1, 3 and 5 min (OH1, OH3 and OH5, respectively). Sarcopenia and its severity were defined according to the revised European consensus on definition and diagnosis.
Results
The mean age of the sample was 75.40 ± 7.35 years, and 69.9% were female. The prevalence of probable sarcopenia, sarcopenia and severe sarcopenia was 42.2%, 6.06% and 11.1%, respectively. After adjustment for all covariates, systolic OH1, OH1 and systolic OH5 were statistically significantly different between severe sarcopenia and the robust group (odds ratio [OR]: 3.26, confidence interval [CI] 0.98–10.84; P = 0.05 for systolic OH1; OR 4.31, CI 1.31–14.15; P = 0.016 for OH1; OR 4.09, CI 1.01–16.55; P = 0.048 for systolic OH5). Only systolic OH1 was statistically different between the sarcopenia and severe sarcopenia groups (OR 2.64, CI 1.87–8.73; P = 0.012). OH1 and OH5 were statistically significant different between severe sarcopenia and probable sarcopenia groups (P < 0.05); there was no relationship between the robust group and probable sarcopenia (P > 0.05).
Conclusions
There is a close relationship between sarcopenia and severe sarcopenia and OH in older adults. Therefore, when a healthcare practitioner is evaluating an older patient with sarcopenia, OH should also be evaluated, and vice versa.</description><identifier>ISSN: 0002-0729</identifier><identifier>EISSN: 1468-2834</identifier><identifier>DOI: 10.1093/ageing/afaa077</identifier><language>eng</language><publisher>Oxford: Oxford University Press</publisher><subject>Blood pressure ; Health care ; Hypotension ; Medical diagnosis ; Older people ; Orthostatic hypotension ; Sarcopenia ; Severity ; Statistical analysis</subject><ispartof>Age and ageing, 2020-11, Vol.49 (6), p.959-965</ispartof><rights>The Author(s) 2020. Published by Oxford University Press on behalf of the British Geriatrics Society. All rights reserved. For permissions, please email: journals.permissions@oup.com 2020</rights><rights>The Author(s) 2020. Published by Oxford University Press on behalf of the British Geriatrics Society. All rights reserved. For permissions, please email: journals.permissions@oup.com</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c440t-62b55bd6ef518acd16beb9abde86b6534f4fa3ccce76fe19ad1d3d2dd8d889903</citedby><cites>FETCH-LOGICAL-c440t-62b55bd6ef518acd16beb9abde86b6534f4fa3ccce76fe19ad1d3d2dd8d889903</cites><orcidid>0000-0002-1124-9720 ; 0000-0001-6078-5469 ; 0000-0002-6042-1718</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,1578,27901,27902,30976</link.rule.ids></links><search><creatorcontrib>Soysal, Pinar</creatorcontrib><creatorcontrib>Kocyigit, Suleyman Emre</creatorcontrib><creatorcontrib>Dokuzlar, Ozge</creatorcontrib><creatorcontrib>Ates Bulut, Esra</creatorcontrib><creatorcontrib>Smith, Lee</creatorcontrib><creatorcontrib>Isik, Ahmet Turan</creatorcontrib><title>Relationship between sarcopenia and orthostatic hypotension</title><title>Age and ageing</title><description>Abstract
Background
The relationship between sarcopenia and orthostatic hypotension (OH) is unclear.
Objectives
The aim of the present study was to investigate associations between sarcopenia/sarcopenia severity and OH.
Design
A total of 511 patients attending a geriatric outpatient clinic were included. OH was defined as a decrease in systolic and/or diastolic blood pressure of ≥ 20 mmHg and/or ≥ 10 mmHg, respectively, when one transitions from the supine to an upright position. OH was measured by the Head-up Tilt Table test at 1, 3 and 5 min (OH1, OH3 and OH5, respectively). Sarcopenia and its severity were defined according to the revised European consensus on definition and diagnosis.
Results
The mean age of the sample was 75.40 ± 7.35 years, and 69.9% were female. The prevalence of probable sarcopenia, sarcopenia and severe sarcopenia was 42.2%, 6.06% and 11.1%, respectively. After adjustment for all covariates, systolic OH1, OH1 and systolic OH5 were statistically significantly different between severe sarcopenia and the robust group (odds ratio [OR]: 3.26, confidence interval [CI] 0.98–10.84; P = 0.05 for systolic OH1; OR 4.31, CI 1.31–14.15; P = 0.016 for OH1; OR 4.09, CI 1.01–16.55; P = 0.048 for systolic OH5). Only systolic OH1 was statistically different between the sarcopenia and severe sarcopenia groups (OR 2.64, CI 1.87–8.73; P = 0.012). OH1 and OH5 were statistically significant different between severe sarcopenia and probable sarcopenia groups (P < 0.05); there was no relationship between the robust group and probable sarcopenia (P > 0.05).
Conclusions
There is a close relationship between sarcopenia and severe sarcopenia and OH in older adults. Therefore, when a healthcare practitioner is evaluating an older patient with sarcopenia, OH should also be evaluated, and vice versa.</description><subject>Blood pressure</subject><subject>Health care</subject><subject>Hypotension</subject><subject>Medical diagnosis</subject><subject>Older people</subject><subject>Orthostatic hypotension</subject><subject>Sarcopenia</subject><subject>Severity</subject><subject>Statistical analysis</subject><issn>0002-0729</issn><issn>1468-2834</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2020</creationdate><recordtype>article</recordtype><sourceid>7QJ</sourceid><recordid>eNqF0M9LwzAUB_AgCs7p1XPBix66JWmaJniS4S8YCKLnkiYvW0eX1KRF9t8b6U5ePD0efL6Pxxeha4IXBMtiqTbQus1SWaVwVZ2gGWFc5FQU7BTNMMY0xxWV5-gixl1aSUnoDN2_Q6eG1ru4bfusgeEbwGVRBe17cK3KlDOZD8PWxyE5nW0PvR_AxRS5RGdWdRGujnOOPp8eP1Yv-frt-XX1sM41Y3jIOW3KsjEcbEmE0obwBhqpGgOCN7wsmGVWFVprqLgFIpUhpjDUGGGEkBIXc3Q73e2D_xohDvW-jRq6TjnwY6wpo5iwUsgq0Zs_dOfH4NJ3SVWcECopTWoxKR18jAFs3Yd2r8KhJrj-7bKeuqyPXabA3RTwY_-f_QFv-Xjx</recordid><startdate>20201101</startdate><enddate>20201101</enddate><creator>Soysal, Pinar</creator><creator>Kocyigit, Suleyman Emre</creator><creator>Dokuzlar, Ozge</creator><creator>Ates Bulut, Esra</creator><creator>Smith, Lee</creator><creator>Isik, Ahmet Turan</creator><general>Oxford University Press</general><general>Oxford Publishing Limited (England)</general><scope>AAYXX</scope><scope>CITATION</scope><scope>7QJ</scope><scope>7T5</scope><scope>7TK</scope><scope>7U9</scope><scope>H94</scope><scope>K9.</scope><scope>NAPCQ</scope><scope>7X8</scope><orcidid>https://orcid.org/0000-0002-1124-9720</orcidid><orcidid>https://orcid.org/0000-0001-6078-5469</orcidid><orcidid>https://orcid.org/0000-0002-6042-1718</orcidid></search><sort><creationdate>20201101</creationdate><title>Relationship between sarcopenia and orthostatic hypotension</title><author>Soysal, Pinar ; Kocyigit, Suleyman Emre ; Dokuzlar, Ozge ; Ates Bulut, Esra ; Smith, Lee ; Isik, Ahmet Turan</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c440t-62b55bd6ef518acd16beb9abde86b6534f4fa3ccce76fe19ad1d3d2dd8d889903</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2020</creationdate><topic>Blood pressure</topic><topic>Health care</topic><topic>Hypotension</topic><topic>Medical diagnosis</topic><topic>Older people</topic><topic>Orthostatic hypotension</topic><topic>Sarcopenia</topic><topic>Severity</topic><topic>Statistical analysis</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Soysal, Pinar</creatorcontrib><creatorcontrib>Kocyigit, Suleyman Emre</creatorcontrib><creatorcontrib>Dokuzlar, Ozge</creatorcontrib><creatorcontrib>Ates Bulut, Esra</creatorcontrib><creatorcontrib>Smith, Lee</creatorcontrib><creatorcontrib>Isik, Ahmet Turan</creatorcontrib><collection>CrossRef</collection><collection>Applied Social Sciences Index & Abstracts (ASSIA)</collection><collection>Immunology Abstracts</collection><collection>Neurosciences Abstracts</collection><collection>Virology and AIDS Abstracts</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Premium</collection><collection>MEDLINE - Academic</collection><jtitle>Age and ageing</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Soysal, Pinar</au><au>Kocyigit, Suleyman Emre</au><au>Dokuzlar, Ozge</au><au>Ates Bulut, Esra</au><au>Smith, Lee</au><au>Isik, Ahmet Turan</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Relationship between sarcopenia and orthostatic hypotension</atitle><jtitle>Age and ageing</jtitle><date>2020-11-01</date><risdate>2020</risdate><volume>49</volume><issue>6</issue><spage>959</spage><epage>965</epage><pages>959-965</pages><issn>0002-0729</issn><eissn>1468-2834</eissn><abstract>Abstract
Background
The relationship between sarcopenia and orthostatic hypotension (OH) is unclear.
Objectives
The aim of the present study was to investigate associations between sarcopenia/sarcopenia severity and OH.
Design
A total of 511 patients attending a geriatric outpatient clinic were included. OH was defined as a decrease in systolic and/or diastolic blood pressure of ≥ 20 mmHg and/or ≥ 10 mmHg, respectively, when one transitions from the supine to an upright position. OH was measured by the Head-up Tilt Table test at 1, 3 and 5 min (OH1, OH3 and OH5, respectively). Sarcopenia and its severity were defined according to the revised European consensus on definition and diagnosis.
Results
The mean age of the sample was 75.40 ± 7.35 years, and 69.9% were female. The prevalence of probable sarcopenia, sarcopenia and severe sarcopenia was 42.2%, 6.06% and 11.1%, respectively. After adjustment for all covariates, systolic OH1, OH1 and systolic OH5 were statistically significantly different between severe sarcopenia and the robust group (odds ratio [OR]: 3.26, confidence interval [CI] 0.98–10.84; P = 0.05 for systolic OH1; OR 4.31, CI 1.31–14.15; P = 0.016 for OH1; OR 4.09, CI 1.01–16.55; P = 0.048 for systolic OH5). Only systolic OH1 was statistically different between the sarcopenia and severe sarcopenia groups (OR 2.64, CI 1.87–8.73; P = 0.012). OH1 and OH5 were statistically significant different between severe sarcopenia and probable sarcopenia groups (P < 0.05); there was no relationship between the robust group and probable sarcopenia (P > 0.05).
Conclusions
There is a close relationship between sarcopenia and severe sarcopenia and OH in older adults. Therefore, when a healthcare practitioner is evaluating an older patient with sarcopenia, OH should also be evaluated, and vice versa.</abstract><cop>Oxford</cop><pub>Oxford University Press</pub><doi>10.1093/ageing/afaa077</doi><tpages>7</tpages><orcidid>https://orcid.org/0000-0002-1124-9720</orcidid><orcidid>https://orcid.org/0000-0001-6078-5469</orcidid><orcidid>https://orcid.org/0000-0002-6042-1718</orcidid><oa>free_for_read</oa></addata></record> |
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| source | Applied Social Sciences Index & Abstracts (ASSIA); EZB-FREE-00999 freely available EZB journals; Alma/SFX Local Collection; Oxford Journals |
| subjects | Blood pressure Health care Hypotension Medical diagnosis Older people Orthostatic hypotension Sarcopenia Severity Statistical analysis |
| title | Relationship between sarcopenia and orthostatic hypotension |
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