Proteomics Analysis Revealed the Importance of Inflammation-Mediated Downstream Pathways and the Protective Role of Curcumin in Bleomycin-Induced Pulmonary Fibrosis in C57BL/6 Mice

Bleomycin (BLM)-induced pulmonary fibrosis is characterized by inflammation in the alveoli, subsequent deposition of extracellular matrix (ECM) and myofibroblasts, and an impaired fibrinolytic system. Here, we describe major hematological changes, the IL-17A-mediated p53-fibrinolytic pathway, and th...

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Veröffentlicht in:Journal of proteome research 2020-08, Vol.19 (8), p.2950-2963
Hauptverfasser: Gouda, Mahesh Manjunath, Rex, D. A. B, ES, Sindhu Priya, Modi, Prashant Kumar, Chanderasekaran, Jaikanth, Bhandary, Yashodhar Prabhakar
Format: Artikel
Sprache:eng
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