Immune related proteins and tumor infiltrating CD8+ lymphocytes in hypopharyngeal cancer in relation to human papillomavirus (HPV) and clinical outcome

Background Hypopharyngeal cancer (HPSCC) shows a poor clinical outcome, while HPSCC, caused by human papillomavirus (HPV), presents a better outcome. Here, HPCC, immune proteins, and tumor infiltrating CD8+ lymphocytes (CD8+ TILs) were evaluated in relation to HPV and outcome. Methods Fresh frozen t...

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Veröffentlicht in:	Head & neck 2020-11, Vol.42 (11), p.3206-3217
Hauptverfasser:	Landin, David, Ährlund‐Richter, Andreas, Mirzaie, Leila, Mints, Michael, Näsman, Anders, Kolev, Aeneas, Marklund, Linda, Dalianis, Tina, Munck‐Wikland, Eva, Ramqvist, Torbjörn
Format:	Artikel
Sprache:	eng
Schlagworte:	Cancer immunotherapy CD8 antigen CD8‐positive lymphocytes Chemokines clinical outcome Clinical outcomes FasL protein Head and neck Human papillomavirus hypopharyngeal cancer Immunohistochemistry Lymphocytes Oncology PD-L1 protein protein expression Proteins Throat cancer Tumors
Online-Zugang:	Volltext
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