Excess tau PET ligand retention in elderly patients with major depressive disorder

Depression is one of the common psychiatric disorders in old age. Major depressive disorder (MDD) has been identified as a risk factor or prodrome for neurodegenerative dementias, suggesting neuropathological overlaps and a continuum between MDD and neurodegenerative disorders. In this study, we exa...

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Veröffentlicht in:	Molecular psychiatry 2021-10, Vol.26 (10), p.5856-5863
Hauptverfasser:	Moriguchi, Sho, Takahata, Keisuke, Shimada, Hitoshi, Kubota, Manabu, Kitamura, Soichiro, Kimura, Yasuyuki, Tagai, Kenji, Tarumi, Ryosuke, Tabuchi, Hajime, Meyer, Jeffrey H., Mimura, Masaru, Kawamura, Kazunori, Zhang, Ming-Rong, Murayama, Shigeo, Suhara, Tetsuya, Higuchi, Makoto
Format:	Artikel
Sprache:	eng
Schlagworte:	631/378 692/699/476/1414 Aged Aged patients Alzheimer's disease Amyloid beta-Peptides Aniline Compounds Behavioral Sciences Biological Psychology Complications and side effects Depressive Disorder, Major - diagnostic imaging Health aspects Humans Ligands Major depressive disorder Measurement Medicine Medicine & Public Health Mental depression Mental disorders Neurodegenerative diseases Neurosciences Older people Patients PET imaging Pharmacotherapy Physiological aspects Positron emission tomography Prognosis Psychiatry Psychosis Risk factors Tau protein Tau proteins β-Amyloid
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