Supramolecular Exchange among Assemblies of Opposite Charge Leads to Hierarchical Structures

Hierarchical assemblies of proteins into fibrillar structures occur in both physiologic and pathologic extracellular spaces and often involve interactions between oppositely charged peptide domains. However, the interplay between tertiary structure dynamics and quaternary hierarchical structure form...

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Veröffentlicht in:J. Am. Chem. Soc 2020-07, Vol.142 (28), p.12216-12225
Hauptverfasser: Wester, James R, Lewis, Jacob A, Freeman, Ronit, Sai, Hiroaki, Palmer, Liam C, Henrich, Stephen E, Stupp, Samuel I
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Sprache:eng
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