The protective effect of ginsenoside Rg1 on depression may benefit from the gap junction function in hippocampal astrocytes

Studies have shown that the ginsenoside Rg1 can improve depressive symptoms in vitro and in vivo. However, the efficacy of Rg1on the hippocampal astrocyte gap junctions in depression are unclear. We mainly aimed to explore the relationship between Rg1, hippocampal astrocyte gap junctions and depress...

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Veröffentlicht in:	European journal of pharmacology 2020-09, Vol.882, p.173309-173309, Article 173309
Hauptverfasser:	Lou, Yu-Xia, Wang, Zhen-Zhen, Xia, Cong-Yuan, Mou, Zheng, Ren, Qian, Liu, Dan-Dan, Zhang, Xin, Chen, Nai-Hong
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Animals, Newborn Antidepressive Agents - pharmacology Antidepressive Agents - therapeutic use Astrocytes - drug effects Astrocytes - metabolism Astrocytes - ultrastructure Cell Survival - drug effects Cells, Cultured Connexin Connexin 43 - metabolism Depression Depression - drug therapy Depression - metabolism Gap junction Gap Junctions - drug effects Gap Junctions - metabolism Gap Junctions - ultrastructure Ginsenoside Rg1 Ginsenosides - pharmacology Ginsenosides - therapeutic use Glial Fibrillary Acidic Protein - metabolism Hippocampus - cytology Male Rats, Sprague-Dawley Stress Stress, Psychological - drug therapy Stress, Psychological - metabolism
Online-Zugang:	Volltext
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