Full-length galectin-8 and separate carbohydrate recognition domains: the whole is greater than the sum of its parts?

Galectin-8 (Gal-8) is a tandem-repeat type galectin with affinity for β-galactosides, bearing two carbohydrate recognition domains (CRD) connected by a linker peptide. The N- and C-terminal domains (Gal-8N and Gal-8C) share 35% homology, and their glycan ligand specificity is notably dissimilar: whi...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Biochemical Society transactions 2020-06, Vol.48 (3), p.1255-1268
Hauptverfasser:	Cagnoni, Alejandro J, Troncoso, María F, Rabinovich, Gabriel A, Mariño, Karina V, Elola, María T
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!