Osteomyelitis Increases the Rate of Amputation in Patients With Type 2 Diabetes and Lower Extremity Burns
Abstract In patients with diabetes mellitus (DM), amputation rates exceed 30% when lower extremity osteomyelitis is present. We sought to determine the rate of osteomyelitis and any subsequent amputation in our patients with DM and lower extremity burns. We performed a single-site, retrospective rev...
Gespeichert in:
Veröffentlicht in: | Journal of burn care & research 2020-09, Vol.41 (5), p.981-985 |
---|---|
Hauptverfasser: | , , , , , |
Format: | Artikel |
Sprache: | eng |
Online-Zugang: | Volltext |
Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
container_end_page | 985 |
---|---|
container_issue | 5 |
container_start_page | 981 |
container_title | Journal of burn care & research |
container_volume | 41 |
creator | Nizamani, Rabia Heisler, Stephen Chrisco, Lori Campbell, Harold Jones, Samuel W Williams, Felicia N |
description | Abstract
In patients with diabetes mellitus (DM), amputation rates exceed 30% when lower extremity osteomyelitis is present. We sought to determine the rate of osteomyelitis and any subsequent amputation in our patients with DM and lower extremity burns. We performed a single-site, retrospective review at our burn center using the institutional burn center registry, linked to clinical and administrative data. Adults (≥18 years old) with DM admitted from January 1, 2014 to December 31, 2018 for isolated lower extremity burns were eligible for inclusion. We evaluated demographics, burn characteristics, comorbidities, presence of radiologically confirmed osteomyelitis, length of stay (LOS), inpatient hospitalization costs, and amputation rate at 3 months and 12 months after injury. We identified 103 patients with DM and isolated lower extremity burns. Of these, 88 patients did not have osteomyelitis, while 15 patients had radiologically confirmed osteomyelitis within 3 months of the burn injury. Compared to patients without osteomyelitis, patients with osteomyelitis had significantly increased LOS (average LOS 22.7 days vs 12.1 days, P = .0042), inpatient hospitalization costs (average $135,345 vs $62,237, P = .0008), amputation rate within 3 months (66.7% vs 5.70%, P < .00001), and amputation rate within 12 months (66.7% vs 9.1%, P < .0001). The two groups were otherwise similar in demographics, burn injury characteristics, access to healthcare, and preexisting comorbidities. Patients with DM and lower extremity burns incurred increased LOS, higher inpatient hospitalization costs, and increased amputation rates if radiologically confirmed osteomyelitis was present within 3 months of the burn injury. |
doi_str_mv | 10.1093/jbcr/iraa106 |
format | Article |
fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_2418726931</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><oup_id>10.1093/jbcr/iraa106</oup_id><sourcerecordid>2418726931</sourcerecordid><originalsourceid>FETCH-LOGICAL-c323t-7a36ae45091f14075a4dc7bfa85c316f9379efe3801b8f792f208a6cd26c83d23</originalsourceid><addsrcrecordid>eNp9kDtPwzAUhS0EoqWwMSNvMBDqR14eSykPqVIRKoItcpxr1VXzwHYE-fekaunIdM_wnaOrD6FLSu4oEXy8zpUdGyslJfERGtIoEgEJ0_T4kJPPATpzbk1IGJIkOkUDziKRiCgeIrNwHuqyg43xxuGXSlmQDhz2K8Bv0gOuNZ6UTeulN3WFTYVf-wSVd_jD-BVedg1ghh-MzMH3PVkVeF5_g8WzH2-hNL7D962t3Dk60XLj4GJ_R-j9cbacPgfzxdPLdDIPFGfcB4nksYQwIoJqun1XhoVKci3TSHEaa8ETARp4Smie6kQwzUgqY1WwWKW8YHyEbna7ja2_WnA-K41TsNnICurWZSykacJiwWmP3u5QZWvnLOissaaUtssoybZys63cbC-3x6_2y21eQnGA_2z2wPUOqNvm_6lfFkyElw</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2418726931</pqid></control><display><type>article</type><title>Osteomyelitis Increases the Rate of Amputation in Patients With Type 2 Diabetes and Lower Extremity Burns</title><source>Oxford University Press Journals All Titles (1996-Current)</source><creator>Nizamani, Rabia ; Heisler, Stephen ; Chrisco, Lori ; Campbell, Harold ; Jones, Samuel W ; Williams, Felicia N</creator><creatorcontrib>Nizamani, Rabia ; Heisler, Stephen ; Chrisco, Lori ; Campbell, Harold ; Jones, Samuel W ; Williams, Felicia N</creatorcontrib><description>Abstract
In patients with diabetes mellitus (DM), amputation rates exceed 30% when lower extremity osteomyelitis is present. We sought to determine the rate of osteomyelitis and any subsequent amputation in our patients with DM and lower extremity burns. We performed a single-site, retrospective review at our burn center using the institutional burn center registry, linked to clinical and administrative data. Adults (≥18 years old) with DM admitted from January 1, 2014 to December 31, 2018 for isolated lower extremity burns were eligible for inclusion. We evaluated demographics, burn characteristics, comorbidities, presence of radiologically confirmed osteomyelitis, length of stay (LOS), inpatient hospitalization costs, and amputation rate at 3 months and 12 months after injury. We identified 103 patients with DM and isolated lower extremity burns. Of these, 88 patients did not have osteomyelitis, while 15 patients had radiologically confirmed osteomyelitis within 3 months of the burn injury. Compared to patients without osteomyelitis, patients with osteomyelitis had significantly increased LOS (average LOS 22.7 days vs 12.1 days, P = .0042), inpatient hospitalization costs (average $135,345 vs $62,237, P = .0008), amputation rate within 3 months (66.7% vs 5.70%, P < .00001), and amputation rate within 12 months (66.7% vs 9.1%, P < .0001). The two groups were otherwise similar in demographics, burn injury characteristics, access to healthcare, and preexisting comorbidities. Patients with DM and lower extremity burns incurred increased LOS, higher inpatient hospitalization costs, and increased amputation rates if radiologically confirmed osteomyelitis was present within 3 months of the burn injury.</description><identifier>ISSN: 1559-047X</identifier><identifier>EISSN: 1559-0488</identifier><identifier>DOI: 10.1093/jbcr/iraa106</identifier><identifier>PMID: 32597956</identifier><language>eng</language><publisher>US: Oxford University Press</publisher><ispartof>Journal of burn care & research, 2020-09, Vol.41 (5), p.981-985</ispartof><rights>The Author(s) 2020. Published by Oxford University Press on behalf of the American Burn Association. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com. 2020</rights><rights>The Author(s) 2020. Published by Oxford University Press on behalf of the American Burn Association. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c323t-7a36ae45091f14075a4dc7bfa85c316f9379efe3801b8f792f208a6cd26c83d23</citedby><cites>FETCH-LOGICAL-c323t-7a36ae45091f14075a4dc7bfa85c316f9379efe3801b8f792f208a6cd26c83d23</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,1578,27901,27902</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/32597956$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Nizamani, Rabia</creatorcontrib><creatorcontrib>Heisler, Stephen</creatorcontrib><creatorcontrib>Chrisco, Lori</creatorcontrib><creatorcontrib>Campbell, Harold</creatorcontrib><creatorcontrib>Jones, Samuel W</creatorcontrib><creatorcontrib>Williams, Felicia N</creatorcontrib><title>Osteomyelitis Increases the Rate of Amputation in Patients With Type 2 Diabetes and Lower Extremity Burns</title><title>Journal of burn care & research</title><addtitle>J Burn Care Res</addtitle><description>Abstract
In patients with diabetes mellitus (DM), amputation rates exceed 30% when lower extremity osteomyelitis is present. We sought to determine the rate of osteomyelitis and any subsequent amputation in our patients with DM and lower extremity burns. We performed a single-site, retrospective review at our burn center using the institutional burn center registry, linked to clinical and administrative data. Adults (≥18 years old) with DM admitted from January 1, 2014 to December 31, 2018 for isolated lower extremity burns were eligible for inclusion. We evaluated demographics, burn characteristics, comorbidities, presence of radiologically confirmed osteomyelitis, length of stay (LOS), inpatient hospitalization costs, and amputation rate at 3 months and 12 months after injury. We identified 103 patients with DM and isolated lower extremity burns. Of these, 88 patients did not have osteomyelitis, while 15 patients had radiologically confirmed osteomyelitis within 3 months of the burn injury. Compared to patients without osteomyelitis, patients with osteomyelitis had significantly increased LOS (average LOS 22.7 days vs 12.1 days, P = .0042), inpatient hospitalization costs (average $135,345 vs $62,237, P = .0008), amputation rate within 3 months (66.7% vs 5.70%, P < .00001), and amputation rate within 12 months (66.7% vs 9.1%, P < .0001). The two groups were otherwise similar in demographics, burn injury characteristics, access to healthcare, and preexisting comorbidities. Patients with DM and lower extremity burns incurred increased LOS, higher inpatient hospitalization costs, and increased amputation rates if radiologically confirmed osteomyelitis was present within 3 months of the burn injury.</description><issn>1559-047X</issn><issn>1559-0488</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2020</creationdate><recordtype>article</recordtype><recordid>eNp9kDtPwzAUhS0EoqWwMSNvMBDqR14eSykPqVIRKoItcpxr1VXzwHYE-fekaunIdM_wnaOrD6FLSu4oEXy8zpUdGyslJfERGtIoEgEJ0_T4kJPPATpzbk1IGJIkOkUDziKRiCgeIrNwHuqyg43xxuGXSlmQDhz2K8Bv0gOuNZ6UTeulN3WFTYVf-wSVd_jD-BVedg1ghh-MzMH3PVkVeF5_g8WzH2-hNL7D962t3Dk60XLj4GJ_R-j9cbacPgfzxdPLdDIPFGfcB4nksYQwIoJqun1XhoVKci3TSHEaa8ETARp4Smie6kQwzUgqY1WwWKW8YHyEbna7ja2_WnA-K41TsNnICurWZSykacJiwWmP3u5QZWvnLOissaaUtssoybZys63cbC-3x6_2y21eQnGA_2z2wPUOqNvm_6lfFkyElw</recordid><startdate>20200923</startdate><enddate>20200923</enddate><creator>Nizamani, Rabia</creator><creator>Heisler, Stephen</creator><creator>Chrisco, Lori</creator><creator>Campbell, Harold</creator><creator>Jones, Samuel W</creator><creator>Williams, Felicia N</creator><general>Oxford University Press</general><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20200923</creationdate><title>Osteomyelitis Increases the Rate of Amputation in Patients With Type 2 Diabetes and Lower Extremity Burns</title><author>Nizamani, Rabia ; Heisler, Stephen ; Chrisco, Lori ; Campbell, Harold ; Jones, Samuel W ; Williams, Felicia N</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c323t-7a36ae45091f14075a4dc7bfa85c316f9379efe3801b8f792f208a6cd26c83d23</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2020</creationdate><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Nizamani, Rabia</creatorcontrib><creatorcontrib>Heisler, Stephen</creatorcontrib><creatorcontrib>Chrisco, Lori</creatorcontrib><creatorcontrib>Campbell, Harold</creatorcontrib><creatorcontrib>Jones, Samuel W</creatorcontrib><creatorcontrib>Williams, Felicia N</creatorcontrib><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of burn care & research</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Nizamani, Rabia</au><au>Heisler, Stephen</au><au>Chrisco, Lori</au><au>Campbell, Harold</au><au>Jones, Samuel W</au><au>Williams, Felicia N</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Osteomyelitis Increases the Rate of Amputation in Patients With Type 2 Diabetes and Lower Extremity Burns</atitle><jtitle>Journal of burn care & research</jtitle><addtitle>J Burn Care Res</addtitle><date>2020-09-23</date><risdate>2020</risdate><volume>41</volume><issue>5</issue><spage>981</spage><epage>985</epage><pages>981-985</pages><issn>1559-047X</issn><eissn>1559-0488</eissn><abstract>Abstract
In patients with diabetes mellitus (DM), amputation rates exceed 30% when lower extremity osteomyelitis is present. We sought to determine the rate of osteomyelitis and any subsequent amputation in our patients with DM and lower extremity burns. We performed a single-site, retrospective review at our burn center using the institutional burn center registry, linked to clinical and administrative data. Adults (≥18 years old) with DM admitted from January 1, 2014 to December 31, 2018 for isolated lower extremity burns were eligible for inclusion. We evaluated demographics, burn characteristics, comorbidities, presence of radiologically confirmed osteomyelitis, length of stay (LOS), inpatient hospitalization costs, and amputation rate at 3 months and 12 months after injury. We identified 103 patients with DM and isolated lower extremity burns. Of these, 88 patients did not have osteomyelitis, while 15 patients had radiologically confirmed osteomyelitis within 3 months of the burn injury. Compared to patients without osteomyelitis, patients with osteomyelitis had significantly increased LOS (average LOS 22.7 days vs 12.1 days, P = .0042), inpatient hospitalization costs (average $135,345 vs $62,237, P = .0008), amputation rate within 3 months (66.7% vs 5.70%, P < .00001), and amputation rate within 12 months (66.7% vs 9.1%, P < .0001). The two groups were otherwise similar in demographics, burn injury characteristics, access to healthcare, and preexisting comorbidities. Patients with DM and lower extremity burns incurred increased LOS, higher inpatient hospitalization costs, and increased amputation rates if radiologically confirmed osteomyelitis was present within 3 months of the burn injury.</abstract><cop>US</cop><pub>Oxford University Press</pub><pmid>32597956</pmid><doi>10.1093/jbcr/iraa106</doi><tpages>5</tpages></addata></record> |
fulltext | fulltext |
identifier | ISSN: 1559-047X |
ispartof | Journal of burn care & research, 2020-09, Vol.41 (5), p.981-985 |
issn | 1559-047X 1559-0488 |
language | eng |
recordid | cdi_proquest_miscellaneous_2418726931 |
source | Oxford University Press Journals All Titles (1996-Current) |
title | Osteomyelitis Increases the Rate of Amputation in Patients With Type 2 Diabetes and Lower Extremity Burns |
url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-31T18%3A47%3A15IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Osteomyelitis%20Increases%20the%20Rate%20of%20Amputation%20in%20Patients%20With%20Type%202%20Diabetes%20and%20Lower%20Extremity%20Burns&rft.jtitle=Journal%20of%20burn%20care%20&%20research&rft.au=Nizamani,%20Rabia&rft.date=2020-09-23&rft.volume=41&rft.issue=5&rft.spage=981&rft.epage=985&rft.pages=981-985&rft.issn=1559-047X&rft.eissn=1559-0488&rft_id=info:doi/10.1093/jbcr/iraa106&rft_dat=%3Cproquest_cross%3E2418726931%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=2418726931&rft_id=info:pmid/32597956&rft_oup_id=10.1093/jbcr/iraa106&rfr_iscdi=true |