Metformin attenuates antipsychotic-induced metabolic dysfunctions in MK801-induced schizophrenia-like rats

Rationale Second-generation antipsychotics are the first-line medications prescribed for schizophrenic patients; however, some of them, such as olanzapine and risperidone, may induce metabolic dysfunctions during short-term treatment. Metformin is an effective adjuvant that attenuates antipsychotic-...

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