Loss-of-Function CREB3L3 Variants in Patients With Severe Hypertriglyceridemia

OBJECTIVE:Genetic determinants of severe hypertriglyceridemia include both common variants with small effects (assessed using polygenic risk scores) plus heterozygous and homozygous rare variants in canonical genes directly affecting triglyceride metabolism. Here, we broadened our scope to detect as...

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Veröffentlicht in:	Arteriosclerosis, thrombosis, and vascular biology thrombosis, and vascular biology, 2020-08, Vol.40 (8), p.1935-1941
Hauptverfasser:	Dron, Jacqueline S., Dilliott, Allison A., Lawson, Arden, McIntyre, Adam D., Davis, Brent D., Wang, Jian, Cao, Henian, Movsesyan, Irina, Malloy, Mary J., Pullinger, Clive R., Kane, John P., Hegele, Robert A.
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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