Covalently Grafted 2‑Methacryloyloxyethyl Phosphorylcholine Networks Inhibit Fibrous Capsule Formation around Silicone Breast Implants in a Porcine Model

The surface of human silicone breast implants is covalently grafted at a high density with a 2-methacryloyloxyethyl phosphorylcholine (MPC)-based polymer. Addition of cross-linkers is essential for enhancing the density and mechanical durability of the MPC graft. The MPC graft strongly inhibits not...

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Veröffentlicht in:	ACS applied materials & interfaces 2020-07, Vol.12 (27), p.30198-30212
Hauptverfasser:	Ham, Jiyeon, Kim, Youngmin, An, Taeyang, Kang, Sunah, Ha, Cheolmin, Wufue, Maierdanjiang, Kim, Yumin, Jeon, Byoungjun, Kim, Seulah, Kim, Jungah, Choi, Tae Hyun, Seo, Ji-Hun, Kim, Dae Woo, Park, Ji-Ung, Lee, Yan
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and Medical Applications of Materials and Interfaces Chemokine CCL4 - metabolism Fibrinogen - chemistry Macrophages - metabolism Methacrylates - chemistry Phosphorylcholine - analogs & derivatives Phosphorylcholine - chemistry Polymers - chemistry Silicones - chemistry Swine
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