p38α Regulates Expression of DUX4 in a Model of Facioscapulohumeral Muscular Dystrophy

Facioscapulohumeral muscular dystrophy (FSHD) is caused by the loss of repression at the D4Z4 locus leading to aberrant double homeobox 4 (DUX4) expression in skeletal muscle. Activation of this early embryonic transcription factor results in the expression of its target genes causing muscle fiber d...

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Veröffentlicht in:	The Journal of pharmacology and experimental therapeutics 2020-09, Vol.374 (3), p.489-498
Hauptverfasser:	Rojas, L. Alejandro, Valentine, Erin, Accorsi, Anthony, Maglio, Joseph, Shen, Ning, Robertson, Alan, Kazmirski, Steven, Rahl, Peter, Tawil, Rabi, Cadavid, Diego, Thompson, Lorin A., Ronco, Lucienne, Chang, Aaron N., Cacace, Angela M., Wallace, Owen
Format:	Artikel
Sprache:	eng
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