Impact of NR5A2 and RYR2 3'UTR polymorphisms on the risk of breast cancer in a Chinese Han population

The NR5A2 and RYR2 genes are important players in steroid metabolism and play an important role in cancer research. In this research, we want to evaluate the effect of NR5A2 and RYR2 polymorphisms on breast cancer (BC). Four single nucleotide polymorphisms on NR5A2 and RYR2 were selected to genotype...

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Veröffentlicht in:	Breast cancer research and treatment 2020-08, Vol.183 (1), p.1-8
Hauptverfasser:	Wei, Ying, Wang, Xiaolin, Zhang, Zhe, Zhao, Changtao, Chang, Yuwei, Bian, Zhiqing, Zhao, Xinhan
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Asian Continental Ancestry Group - genetics Breast cancer Breast Neoplasms - chemistry Breast Neoplasms - ethnology Breast Neoplasms - genetics Breast Neoplasms - pathology Cancer Case-Control Studies China - epidemiology Disease Resistance - genetics Disease susceptibility Estrogen Estrogens Ethnic Groups - genetics Female Genes Genetic aspects Genetic Predisposition to Disease Genotype Health aspects Humans Incidence Metastasis Middle Aged Models, Genetic Neoplasm Metastasis Neoplasm Proteins - analysis Neoplasm Staging Neoplasms, Hormone-Dependent - ethnology Neoplasms, Hormone-Dependent - genetics Odds Ratio Oncology, Experimental Physiological aspects Polymorphism, Single Nucleotide Progesterone Receptor, ErbB-2 - analysis Receptors, Cytoplasmic and Nuclear - genetics Receptors, Cytoplasmic and Nuclear - physiology Receptors, Estrogen - analysis Receptors, Progesterone - analysis Risk Risk factors Ryanodine Receptor Calcium Release Channel - genetics Ryanodine Receptor Calcium Release Channel - physiology Single nucleotide polymorphisms
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