Semen Brassicae reduces thoracic aortic remodeling, inflammation, and oxidative damage in spontaneously hypertensive rats

This study aimed to evaluate the role of Semen Brassicae, a common Traditional Chinese Medicine, in the treatment of hypertension. Spontaneously hypertensive rats (SHRs) were divided into five groups and were gavaged with either distilled water, water-decocted solution from Semen Brassicae (0.5, 1 o...

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Veröffentlicht in:	Biomedicine & pharmacotherapy 2020-09, Vol.129, p.110400-110400, Article 110400
Hauptverfasser:	Lin, Fengxia, Huang, Xiaojing, Xing, Fuya, Xu, Luhua, Zhang, Weiwei, Chen, Zhengtao, Ke, Xiao, Song, Yinzhi, Zeng, Zhicong
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Anti-Inflammatory Agents - isolation & purification Anti-Inflammatory Agents - pharmacology Antihypertensive Agents - isolation & purification Antihypertensive Agents - pharmacology Antioxidants - isolation & purification Antioxidants - pharmacology Aorta, Thoracic - drug effects Aorta, Thoracic - metabolism Aorta, Thoracic - pathology Aorta, Thoracic - physiopathology Blood Pressure - drug effects Disease Models, Animal Drugs, Chinese Herbal - isolation & purification Drugs, Chinese Herbal - pharmacology Hypertension - drug therapy Hypertension - metabolism Hypertension - pathology Hypertension - physiopathology Inflammation Inflammation Mediators - metabolism Male NF-kappa B - metabolism Oxidative stress Oxidative Stress - drug effects Rats, Inbred WKY Rats, Sprague-Dawley Seeds Semen Brassicae Signal Transduction Sinapis - chemistry Spontaneously hypertensive rats Vascular remodeling Vascular Remodeling - drug effects
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