Population-based Screening for BRAF V600E in Metastatic Colorectal Cancer Reveals Increased Prevalence and Poor Prognosis

mutations portend poor prognosis in metastatic colorectal cancer (mCRC); however, the true prevalence and prognosis are unknown, as unwell patients may not undergo sequencing. We reviewed a population-based cohort of 1,898 patients with colorectal cancer that underwent reflexive IHC mismatch repair...

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Veröffentlicht in:Clinical cancer research 2020-09, Vol.26 (17), p.4599-4605
Hauptverfasser: Chu, Jenny E, Johnson, Benny, Kugathasan, Laveniya, Morris, Van K, Raghav, Kanwal, Swanson, Lucas, Lim, Howard J, Renouf, Daniel J, Gill, Sharlene, Wolber, Robert, Karsan, Aly, Kopetz, Scott, Schaeffer, David F, Loree, Jonathan M
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Sprache:eng
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