Adjunctive perampanel and myoclonic and absence seizures: Post hoc analysis of data from study 332 in patients with idiopathic generalized epilepsy

•We assessed myoclonic and absence seizure outcomes with perampanel from Study 332.•Add-on perampanel and placebo reduced myoclonic and absence seizure frequency.•Treatment-emergent adverse events were consistent with perampanel’s safety profile.•Outcomes were maintained during long-term (>104 we...

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Veröffentlicht in:	Seizure (London, England) England), 2020-08, Vol.80, p.115-123
Hauptverfasser:	Brandt, Christian, Wechsler, Robert T., O’Brien, Terence J., Patten, Anna, Malhotra, Manoj, Ngo, Leock Y., Steinhoff, Bernhard J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Absence seizures Anticonvulsants - therapeutic use Double-Blind Method Drug Therapy, Combination Epilepsy, Generalized - drug therapy Humans Idiopathic generalized epilepsy Myoclonic seizures Nitriles Open-label extension Perampanel Pyridones - adverse effects Seizure-free days Seizures - drug therapy Treatment Outcome
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