Short inter-pregnancy interval and pregnancy-associated breast cancer

The relationship between pregnancy and breast cancer risk is not fully understood. Most of the literature has described this interaction in terms of the age at first pregnancy and the number of full-term pregnancies. During the prospective accrual of the “Joven & Fuerte: Program for young women...

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Veröffentlicht in:Medical hypotheses 2020-11, Vol.144, p.109951-109951, Article 109951
Hauptverfasser: Diaz-Perez, Hector M., Mesa-Chavez, Fernanda, Lopez-Martinez, Edna A., Villarreal-Garza, Cynthia
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container_start_page 109951
container_title Medical hypotheses
container_volume 144
creator Diaz-Perez, Hector M.
Mesa-Chavez, Fernanda
Lopez-Martinez, Edna A.
Villarreal-Garza, Cynthia
description The relationship between pregnancy and breast cancer risk is not fully understood. Most of the literature has described this interaction in terms of the age at first pregnancy and the number of full-term pregnancies. During the prospective accrual of the “Joven & Fuerte: Program for young women with breast cancer in Mexico” cohort, a series of cases with pregnancy-associated breast cancer and a history of a short inter-pregnancy interval was identified. To date, there is a very limited number of descriptions about the interaction between a short inter-pregnancy interval and breast cancer, but none specifically regarding the association of a short inter-pregnancy interval and pregnancy-associated breast cancer. Based on findings from a prospective cohort of young Mexican breast cancer patients, we hypothesize that a short inter-pregnancy interval may increase the incidence of pregnancy-associated breast cancer, possibly by amplifying the effects of the pregnancy-associated factors involved in the development of breast cancer.
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subjects Birth Intervals
Breast cancer
Breast Neoplasms - epidemiology
Female
Humans
Incidence
Mexico
Pregnancy
Pregnancy-associated breast cancer
Prospective Studies
Risk Factors
Short inter-pregnancy interval
Young
title Short inter-pregnancy interval and pregnancy-associated breast cancer
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