A Case of Extensive Debilitating Generalized Morphea

Morphea, also known as localized scleroderma, is an uncommon idiopathic inflammatory disorder leading to the development of sclerotic plaques in the skin. The disorder preferentially affects females. The pathogenesis of morphea is not well-understood. The disorder is likely to have an autoimmune bas...

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Veröffentlicht in:Cureus 2020, Vol.12 (5), p.e8117-e8117
Hauptverfasser: Sapra, Amit, Dix, Rebecca, Bhandari, Priyanka, Mohammed, Asiya, Ranjit, Eukesh
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container_issue 5
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container_title Cureus
container_volume 12
creator Sapra, Amit
Dix, Rebecca
Bhandari, Priyanka
Mohammed, Asiya
Ranjit, Eukesh
description Morphea, also known as localized scleroderma, is an uncommon idiopathic inflammatory disorder leading to the development of sclerotic plaques in the skin. The disorder preferentially affects females. The pathogenesis of morphea is not well-understood. The disorder is likely to have an autoimmune basis; environmental and genetic factors may also play a role in its etiology. Morphea has a variety of clinical presentations. Lesions of morphea typically begin as inflammatory plaques or patches that evolve into firm sclerotic lesions. Involvement may be limited to the dermis or may extend to underlying subcutaneous fat, muscle, or bone. The identification of characteristic clinical findings is often sufficient for the diagnosis of morphea. A biopsy can be a useful tool when the diagnosis is in question or to obtain information on the depth and intensity of the disease, and it should always extend at least into the subcutaneous fat. Morphea may cause joint contractures and other impairments secondary to tissue sclerosis and can be very debilitating cosmetically and functionally.
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title A Case of Extensive Debilitating Generalized Morphea
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