Quantification of imatinib and related compounds using capillary electrophoresis‐tandem mass spectrometry with field‐amplified sample stacking

A quantification method for imatinib (IM), its major metabolite N‐desmethyl imatinib (NDI), and a degradation by‐product was developed using CE–MS combined with an online concentration technique. The use of multiple reaction monitoring (MRM)–MS/MS further improved the sensitivity of this technology....

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