Interplay of Pyrrolidine Units with Homo/Hetero Chirality and CF3–Aryl Substituents on Secondary Structures of β‑Proline Tripeptides in Solution

All possible variants of β-proline functionalized tripeptides consisting of homo/hetero chiral monomeric all-cis 5-arylpyrrolidine-2,4-dicarboxylate units were synthesized for the first time by a nonpeptidic coupling method based on 1,3-dipolar cycloaddition chemistry of azomethine ylides. Secondary...

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Veröffentlicht in:Journal of organic chemistry 2020-07, Vol.85 (14), p.8865-8871
Hauptverfasser: Mantsyzov, Alexey B, Sokolov, Mikhail N, Ivantcova, Polina M, Bräse, Stefan, Polshakov, Vladimir I, Kudryavtsev, Konstantin V
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Sprache:eng
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