Genomic DNA methylation in HLA-Cw0602 carriers and non-carriers of psoriasis

•HLA-Cw*0602 is an important genetic biomarker in psoriasis (Ps).•Epigenetic changes, specifically the methylation contributed to the development of Ps.•Key methylation sites contributed to the carrying status of HLA-Cw*0602 were evaluated.•Methylation loci in gene body and CGI may affect the methyl...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Journal of dermatological science 2020-07, Vol.99 (1), p.23-29
Hauptverfasser:	Tang, Lili, Yao, Tianyu, Fang, Miaohong, Zheng, Xiaodong, Chen, Gang, Li, Mengqing, Wang, Dan, Li, Xinyu, Ma, Haining, Wang, Xiangru, Qian, Yunhong, Zhou, Fusheng
Format:	Artikel
Sprache:	eng
Schlagworte:	Alleles Biomarkers CpG Islands - genetics DNA Methylation Epigenesis, Genetic Genetic Predisposition to Disease Genome-Wide Association Study Genotyping Techniques Heterozygote HLA Imputation HLA-C Antigens - genetics HLA-C Antigens - immunology HLA-Cw0602 Humans Psoriasis Psoriasis - diagnosis Psoriasis - genetics Psoriasis - immunology Psoriasis - pathology Skin - immunology Skin - pathology Whole Genome Sequencing
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!