Low expression of miR-20b-5p indicates favorable prognosis in laryngeal squamous cell carcinoma, especially in patients with non-infiltrated regional lymph nodes

Tumor recurrence and distant metastasis are very common in laryngeal squamous cell carcinoma (LSCC). In this study, we examined the potential prognostic value of microRNA-20b-5p (miR-20b-5p), a component of the tumor-related miR-106a/363 cluster. Total RNA was purified from 105 tissue specimens rese...

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Veröffentlicht in:	American journal of otolaryngology 2020-09, Vol.41 (5), p.102563-102563, Article 102563
Hauptverfasser:	Pantazis, Theodwros-Leonidas, Giotakis, Aris I., Karamagkiolas, Sotirios, Giotakis, Ioannis, Konstantoulakis, Manousos, Liakea, Aliki, Misiakos, Evangelos P.
Format:	Artikel
Sprache:	eng
Schlagworte:	Biomarkers Cancer Gene expression Head & neck cancer Head and neck cancer Hypoxia Laryngeal cancer Larynx Lymph nodes Lymphatic system Medical prognosis Metastases microRNA (miRNA) MicroRNAs miRNA Molecular tumor biomarker Polyadenylation Polymerase chain reaction Prognosis Prognostic biomarker Real-time quantitative PCR Regression analysis Reverse transcription Ribonucleic acid RNA Squamous cell carcinoma Subgroups Survival analysis Tumors
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